Unexpected Histopathological Diagnoses in Acute Appendicitis Specimens: A Retrospective Analysis of 2076 Patients
Journal Title: Turkish Journal of Colorectal Disease - Year 2020, Vol 30, Issue 3
Abstract
Aim: Acute appendicitis is the most common cause of emergency abdominal surgery in the world. Although the etiology of appendicitis is still not fully known, possible causes include lumen obstruction. Fecaloid and lymphoid hyperplasia are the most common causes of lumen obstruction. However, some rare conditions may cause acute appendicitis by causing lumen obstruction. Here, we aimed to present the pathology results of 2076 patients operated due to acute appendicitis in our hospital and the unexpected histopathological findings in the light of the literature. Method: Patients who were emergently operated with diagnosis of appendicitis between January 2016 and February 2020 in Gaziantep Dr. Ersin Arslan Training and Research Hospital were retrospectively screened. Incidental appendectomies were excluded. Data of 2076 patients were reached. Gender, age, and pathology results of the patients were analyzed. Pathology preparations were reassessed by two pathologists. Pathology results were analyzed under two categories as general findings and unexpected findings. Fisher’s chi-square test was used for statistical analysis. Results: A total of 2076 patients were included in the study and analyzed. Of the patients, 1368 (66%) were man, 708 (34%) were woman, and the mean age was 33±12.9 years. Acute appendicitis was found in 1309 (63.1%) patients, gangrenous-perforated appendicitis in 305 (14.7%) patients, negative appendectomy in 105 (5.1%) patients, phlegmonous appendicitis in 32 (1.5%) patients, and unexpected pathological findings in 62 (3%) patients. Among the unexpected pathological findings were fibrous obliteration in 31 (50%) patients, mucosal hyperplasia in 8 (13%) patients, appendicular diverticulitis in 7 (11.3%) patients, retention cyst in 5 (8.1%) patients, mucinous cystadenoma in 3 (4.8%) patients, well-differentiated neuroendocrine tumor in 2 (3.2%) patients, eosinophilic infiltration in 2 (3.2%) patients, foreign body reaction in 2 (3.2%) patients, granulomatous appendicitis in 1 (1.6%) patient, and parasitic infestation was detected in 1 (1.6%) patient. Conclusion: Unexpected histopathological findings are rare in appendectomy specimens and these diagnoses help guide the patient’s treatment.
Authors and Affiliations
Ufuk Uylaş, Ramazan Gündoğdu, Kazım Gemici, Marina Tsaplina, Dila Ayerden
Keywords
Related Articles
- EP ID EP688612
- DOI 10.4274/tjcd.galenos.2020.2020-3-1
- Views 163
- Downloads 0
Type 4 Congenital Pouch Colon without Fistula with Anal Agenesis and Lower Vaginal Agenesis in a Female Fetus: A Rare Autopsy Case Report
Congenital pouch colon is a rare anorectal malformation of unknown embryogenesis in which all or part of the large intestine is replaced by a pouch-like dilatation that usually communicates with the urogenital tract via...
Comparison of V-Y Flap and Limberg Flap Methods in Pilonidal Sinus Surgery
Aim: The aim of this study was to compare the advantages of V-Y flap and Limberg flap techniques in the surgical management of complicated pilonidal sinus disease requiring extensive excision, and to review the superiori...
Robotic Low Anterior Resection and TAH+BSO with Transvaginal NOSE
In the last century, laparoscopic interventions have been developed to minimize the somatic and phsiological effects of surgery. Laparoscopic approaches have become frequently used in colorectal surgery as well. In recen...
Learning Curve at Laparoscopic Colorectal Surgery
Aim: The learning curve at laparoscopic colorectal surgery is a long and laborious process. Therefore, despite its advantages, it cannot still be accepted as the gold standard procedure. The purpose of this study is to c...
Prospective Comparison of the Efficacy of Two Common Appendicitis Scoring Systems: Is Combination a Solution?
Aim: The diagnosis of acute appendicitis mostly relies on history taking and physical examination findings supported by laboratory and imaging studies. A number of different diagnostic scoring systems have been developed...