Urothelial Carcinoma of the Upper Urinary Tract That Becomes Resectable After Neoadjuvant Chemotherapy: A Case Report and Review of the Literature
Journal Title: Journal of Urological Surgery - Year 2021, Vol 8, Issue 1
Abstract
Upper tract urothelial carcinoma (UTUC) is less common than bladder cancer, but its incidence is increasing. Neoadjuvant chemotherapy (NAC) has been the treatment focus for locally invasive and high-grade UTUC. Herein, we aimed to present a case of a locally advanced non-metastatic UTUC, which was thought to be unresectable due to local invasion, but surgically treated successfully after NAC. A 64-year-old male patient was admitted to another hospital because of right flank pain, which was not accompanied by macroscopic haematuria. He did not have comorbidities in his anamnesis, but he had a history of smoking 40 packs/year. A locally invasive right kidney tumour was detected in cross-sectional imaging performed at another hospital. He underwent surgery in that hospital, but radical nephroureterectomy could not be performed because of local invasion. He presented to our urology department. He was subsequently started with cisplatin-based NAC, which led to the resolution of local invasion. After NAC, right radical nephroureterectomy and ipsilateral bladder cuff excision with subcostal and Gibson incisions were performed. No signs of mass invasion or lymph node involvement were detected intraoperatively. He was examined 3 months after surgery. On cystourethroscopy, the bladder was normal and cytology was benign. No recurrence or metastasis was detected on the whole-body computed tomography. NAC is one of the valuable multimodal treatment options, enables surgery in locally invasive UTUC and contributes positively to survival rate.
Authors and Affiliations
Mustafa Dinçkal, Fuat Kızılay, Serdar Kalemci, Adnan Şimşir
Keywords
Related Articles
- EP ID EP693419
- DOI 10.4274/jus.galenos.2020.4025
- Views 99
- Downloads 0
From the Scalpel to the Water
No summary
A Unique Representation of Female Urinary Catheter in Ancient Roman Art
Abstract(s)*
A Modified Surgical Technique Using Cyanoacrylate Glue and Parenchymal Restoration Sutures without Tissue Approximation in Patients with Renal Tumors Who Underwent Open Partial Nephrectomy
Objective: To investigate the results of a modified open partial nephrectomy technique by using cyanoacrylate glue after the parenchymal restoration sutures without performing tissue reapproximation and to compare compli...
Global Publication Outcomes in Retrograde Intrarenal Surgery and Turkiye’s Effectiveness: A Bibliometric Analysis between 1980 and 2019
Objective: Urinary system stone disease is a very common health problem that affects 2 to 3% of people and causes serious complications when it is not treated. The prevalence of renal stones has been increasing worldwide...
Bacterial Colonization of Ureteral Double-J Stents in Patients with Negative Urine Culture
Objective: Ureteral double-J stents are extensively used in urology practice. We aimed to investigate the bacterial colonization rate and predominant microorganisms on ureteral double-J stents in patients with negative u...