USE OF ATRACURIUM AND ITS REVERSAL BY ANAESTHESIOLOGISTS AT A TERTIARY CARE HOSPITAL
Journal Title: International Research Journal of Pharmacy (IRJP) - Year 2013, Vol 4, Issue 3
Abstract
Atracurium Besylate is a non-depolarizing neuromuscular blocking agent. The aim of this study was to determine the practice trends for the use of reversal agent after atracurium by anaesthesiologists. A structured questionnaire was designed to know the practice of anaesthesiologists using reversal agent in patients who have undergone general anaesthesia and were given the intermediate acting neuromuscular blocker atracurium. Ninety nine percent participants used atracurium as a common neuromuscular blocking agent. 83.6% used the reversal agent after atracurium in every patient whereas 16.4 % used it in selected patients. In our institution most of the anaesthesiologists use reversal agent after atracurium in every patient as it is a general belief that not using reversal will prolong the recovery time, despite the fact that the use of reversal agent is debatable all over the world. Further study should be carried out to know the practice trends of rest of the anaesthesiologists as well as to evaluate the effective recovery following the single dose or infusion of atracurium and the need of reversal agent.
Authors and Affiliations
Asma Abdus, Gauhar Afshan
THE EFFECT OF pH CONTROL ON THE SOLUBILITY AND PARTITION COEEFICIENT OF TRANDOLAPRIL
The objective of the present study was to investigate the effect of pH control on the aqueous solubility and partition coefficient of trandolapril respectively. The aqueous solubility was determined at 25 ° C using pH va...
EMULSION TECHNOLOGY AND RECENT TRENDS IN EMULSION APPLICATIONS
Emulsions are thermodynamically unstable heterogeneous biphasic system. There are certain parameters which if and emulsion follow considered as stable. There are lots of sign of physical and chemical instability of emuls...
EFFECT OF KONDAGOGU ON THE RELEASE BEHAVIOUR OF AMBROXOL HYDROCHLORIDE MATRIX TABLETS
The aim of present research work was to study the effect of kondagogu on the release behavior of ambroxol hydrochloride sustained delivery dosage forms. Oral dosage forms containing 75mg Ambroxol hydrochloride in matrix...
REVIEW / PHARMACOLOGICAL ACTIVITY OF PLATYCLADUS ORIEANTALIS
Platycladus orientalis, also known as Chinese Arborvitae or Biota. It is native to northwestern China and widely naturalized elsewhere in Asia east to Korea and Japan, south to northern India, and west to northern Iran....
ROLE OF VARIOUS OPIOID RECEPTORS IN OPIOID DEPENDENCE AND WITHDRAWAL SYNDROME
Although dependence liability of opioids is widely recognized, the relative involvement of different opioid receptors mediating physical dependence is not completely known. The present study was aimed to explore the role...