Use of Topical Cyclosporine A 0.05% in Treatment of Adenoviral Keratoconjunctivitis-Related Subepithelial Infiltrates
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2019, Vol 18, Issue 1
Abstract
Aim : To evaluate the treatment with topical cyclosporine A (CsA) in patients with subepithelial infiltrates (SEI). Material & Methods: Hospital-based study was conducted over a period of one year. A total of 25 patients, 36 eyes with supepithelial infiltrates following adenoviral keratoconjunctivitis were included in the study. All patients had been previously treated with topical corticosteroids without any improvement. Data was recorded in form of best corrected visual acuity (BCVA), evaluation of corneal subepithelial infiltrate score (CSIS) prior to treatemt and after the last follow up visit. Results:10 females(40 %) and 15 males (60 %) were included in the study, best corrected visual acuity (BCVA) was in range 6/6-6/60 pre-treatement and 6/6-6/18 after treatment.The average followup in patients was after 4- 6 months. After treatment with 0.05 % topical CsA, 28 eyes (77 %) improved to 0 score on CSIS and BCVA of 6/6 in 27 eyes while recurrence occurred in 6 eyes (16.6 %). Conclusion: Topical Cyclosporine A 0.05% is a safe and effective alternative treatment in patients with adenoviral keratoconjunctivitis -related subepithelial infiltrates.
Authors and Affiliations
Dr Harvinder Nagpal, Dr Mandeep Kaur
Keywords
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- EP ID EP440488
- DOI 10.9790/0853-1801114244.
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