Usefulness and limitations of core biopsy in pancreatic tumors diagnostics – retrospective analysis
Journal Title: Postępy Nauk Medycznych - Year 2015, Vol 28, Issue 5
Abstract
Introduction. Pancreatic lesions may be diagnosed with imaging techniques and invasive procedures (evaluating tissue material obtained intraoperatively, by laparoscopy or percutaneous biopsy). One of the methods to take tissue samples for futher diagnostics is core biopsy.Aim. Purpose of this study is to analyze frequency and type of complications after using core needles (16, 18, 20 G) for pancreatic lesions biopsy.Material and methods. Between 2010 and 2014 in Radiology Department, Medical University of Gdańsk, 46 core biopsies of pancreatic lesions in 26 patients were performed.Procedures were monitored under CT scopy in 4 patients, and in 22 patients under the guidance of ultrasound. In local analgesia and under 50 mg Dolargan premedication 1 to 3 fragments were taken and preserved in formalin.Results. Obtained material in all patients permitted to set the diagnosis: 15 patients were diagnosed with adenocarcinomas pancreatis, 3 with neuroendocrine tumours, 4 patients with benign lesions (adenoma, retentive cyst) and in lasting 4 patients presence of neoplasm was not confirmed.We observed early complications such as: pain, bleeding from puncture site, nausea. During 24 h observation after biopsy one pancreato-peritoneal fistula was noted, one acute pancreatitis, one prolonged bleeding with haematoma. All patients except one were treated conservatively. In this one patient few consecutive laparotomias were performed, with unsuccessfull attempts to repair the fistula, which eventually was treated with endoscopic drainage.Conclusions. Pancreatic core biopsy is a safe method, allowing to set in majority of patients precise histopathological diagnosis, which is essential to start proper oncologic treatment. Small percentage of complications – mainly pain during the procedure – are not a significant reason for introducing additional treatment.
Authors and Affiliations
Katarzyna Gwoździewicz, Joanna Pieńkowska, Przemysław Szlęzak, Monika Czarnowska-Cubała, Karolina Markiet, Tomasz Gorycki, Michał Studniarek
Keywords
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