Using Pazopanib and Radiotherapy to Treat Metastatic Renal Cell Carcinoma with Acrometastases

Abstract

Introduction: Renal cell carcinoma (RCC) is the third most common urological cancer. Skeletal metastases from renal cell carcinoma are common, but metastatic tumors involving the hand and foot are rare. This is known as acrometastases and is usually a late manifestation ofdisseminated disease. Case: We present a metastatic case of RCC with acrometastases. Pazopanib treatment was started and there was a quick but short-term response. The patient refused to have surgery for hand lesions so radiotherapy was given. The patient is in good health and under pazopanib treatment. Conclusion: RCC patients with acral metastases have a short median survival and a choice of treatment should be made considering this poor prognosis. Surgery is the usual choice for treatment. However, if there are multiple digital metastases the quality of life of the patient should be taken into account. Palliative radiotherapy and pazopanib helped our patient and improved his quality of life.

Authors and Affiliations

Cigdem Usul Afsar, Semra Paydas

Keywords

Related Articles

Small Bowel Adenocarcinoma in a Nigerian Man: A Case Report

Malignancies of the small bowel are a rare occurrence with a worldwide incidence of less than 1.0 per 100,000 populations. Only 2% of the total annual incidence of digestive cancers occurs in the small intestine as compa...

Thyroid Hyalinizing Trabecular Tumor: A Case Series

Aim: Hyalinizing Trabecular Tumor (HTT) of the thyroid gland is an unusual and rare follicular derived neoplasm, which was first described from Carney and colleagues in 1987. We aim to present two cases of HTT diagnosed...

Vitamin D Status among Egyptian Mothers and Their Neonates: An Exploratory Study

Background/Objective: The potential impact of vitamin D deficiency during pregnancy has attracted much interest in recent years. This study was an exploratory one aimed to assess vitamin D status among a small random sam...

Gingival Overgrowth Associated with Phenytoin Therapy: Report of a Case

Gingival overgrowth (also called gingival hyperplasia, or gingival hypertrophy) refers to an increase in the size of the gingiva. It is seen as an adverse effect of drugs such as anticonvulsants, immunosuppressants, and...

Hidradenitis Suppurativa: Two-case Reports

Hidradenitis suppurativa (HS) is a common (though rarely diagnosed) disease affecting the apocrine glands. It is chronic in nature and mainly found in areas rich in apocrine glands like axillae, groins, under the breast,...

Download PDF file
  • EP ID EP343681
  • DOI 10.9734/IJMPCR/2015/17236
  • Views 85
  • Downloads 0

How To Cite

Cigdem Usul Afsar, Semra Paydas (2015). Using Pazopanib and Radiotherapy to Treat Metastatic Renal Cell Carcinoma with Acrometastases. International Journal of Medical and Pharmaceutical Case Reports, 4(2), 50-53. https://europub.co.uk/articles/-A-343681