Utility of fine needle aspiration cytology (FNAC) in the diagnosis of soft tissue tumors and tumor like lesions
Journal Title: Indian Journal of Pathology and Oncology - Year 2018, Vol 5, Issue 2
Abstract
Introduction Fine needle aspiration cytology FNAC forms one of the first diagnostic tools in evaluation of soft tissue lesions Aim of this study was to evaluate the role of FNAC in the primary diagnosis of soft tissue tumors and tumor like lesions and to assess the effectiveness of FNAC in the histological subtyping and grading of soft tissue tumorsMaterials and Methods We reviewed FNAC smears of 170 soft tissue tumors and tumor like lesions over a 3 years period and correlated with the histopathological features which were available in 117 cases Conventional Papanicolaou PAP and Giemsa staining was done in all casesResults 152 out of 170 cases 8941 were neoplastic of which 130 tumors were labelled as benign Lipoma constituted 8307 of benign tumors Based on the predominant cytomorphological features and background the tumors were classified into myxoid 4 spindle cell 20 pleomorphic 2 small round cell4 epithelioid polygonal cell 7 lipomatous 108 and miscellaneous 7 The nonneoplastic lesions included tuberculosis filariasis actinomycosis scar endometriosis and calcinosis cutisConclusion FNAC proved to be helpful in distinguishing between neoplastic and nonneoplastic soft tissue lesions differentiating metastatic carcinoma and melanoma in soft tissue from primary soft tissue tumors and differentiating benign and malignant soft tissue tumors Accurate subtyping was possible in many tumors of myxoid category and round cell tumors Spindle cell tumors of intermediate grade were difficult to grade on FNAC Pleomorphic sarcomas were of high grade and their subtyping could not be done on FNACKeywords FNAC Soft tissue lesions Soft tissue tumors
Authors and Affiliations
Anitha Padmanabhan, Sonali Rajesh Saraf, Vandita Singh, Nikita Anil Patel
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