UTILITY OF SERUM FREE CALCIUM AS A PREDICTOR OF SEVERITY IN DENGUE FEVER
Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2018, Vol 7, Issue 39
Abstract
BACKGROUND Dengue fever causes considerable mortality and morbidity. The calcium ion plays a major role in cellular functions and signalling. We evaluated the correlation between severity of dengue and the serum free calcium. MATERIALS AND METHODS A cross-sectional study was done in a tertiary care hospital in Bapuji and Chigateri Hospital, Davangere. Patients with dengue fever were diagnosed using NS1 antigen and/or IgM antibody tests and were classified according to WHO criteria. The association between severity of dengue and serum free calcium was studied. RESULTS Sample size was 100. Among them, 68 (68%) were males and 32 (32%) were females. 37 (37%), 54 (54%) and 9 (9%) patients were classified as Dengue Fever (DF), Dengue Fever with Warning Signs (DF + WS) and Severe Dengue (SD) respectively. The mean serum free calcium in the study was 3.92 ± 0.50 mg/dL. The mean serum calcium (mg/dL) in each class were as follows- Severe Dengue (3.09 ± 0.16), Dengue Fever with Warning Signs (3.72 ± 0.34) and Dengue Fever (4.41 ± 0.16). The presence of hypocalcaemia significantly correlated with the severity of dengue (p < 0.001). CONCLUSION We conclude that the serum free calcium levels significantly correlated with the severity of dengue fever. Serum free calcium can be used as a predictor of severity in dengue fever.
Authors and Affiliations
Suresh S. R, Srikanth A. K, K. Sriharsha, Harshith C. S
Keywords
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- EP ID EP548149
- DOI 10.14260/jemds/2018/954
- Views 71
- Downloads 0
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