Utility of stroke scores in correctly diagnosing stroke subtype and starting low risk antithromotic therapy in areas without imaging facilities
Journal Title: MedPulse -International Medical Journal - Year 2017, Vol 4, Issue 1
Abstract
Background and Objective: Stroke burden in India and all over the world is already high and is increasing, but limited patients with stroke have access to brain imaging. Distinguishing pathologic stroke types is relevant both for clinical management and epidemiologic studies. We assessed the accuracy of two stroke scores which are based on clinicians assessment of patient in distinguishing stroke subtypes and compared them with the computed tomography brain scanning as the “gold standard.” Methodology: This comparative, analytical study was conducted at Shri. V.N. Govt. Medical College, from December 2012 to July 2015. Study included 150 consecutive patients of acute stroke admitted to our hospital. ASS and SSS were calculated for each patient and compared with the results of CT scan(sensitivity, specificity, positive predictive value, likelihood ratio, kappa statistics). Results: Out of 150 patients, 105 had CI and 45 had CH. The overall comparability of ASS and SSS was good (Kappa=0.728). SSS was equivocal in 5 cases. The sensitivity, specificity, positive predictive value (PPV) and negative predictive value (NPV) of SSS was 87.62%; 84.44%; 92.93% and74.51% respectively for CI and 82..22%, 87.62%, 74% and 92% respectively for CH. The sensitivity, specificity, PPV and NPV of ASS was 87.62%, 73.33%, 88.46% and 71.74% respectively for CI and 73.33%, 87.62%, 71.74% and 88.46% respectively for CH. Conclusion: Although, SSS simple to calculate and being more accurate is better than ASS, both these scores lack sufficient validity to be used for exclusion of intracerebral hemorrhage so cannot be used to offer high risk thrombolytic therapy.
A study of severity of malaria with reference to thrombocytopenia
Introduction: Malarial infection reported as early as 1570 BC from Egypt still at times poses a diagnostic and therapeutic challenge in this modern anti- microbial era . All over the world fever has traditionally been re...
Post injection site extensive fungal infection: A rare case report and review
Mucormycoses are high-mortality infections feared by clinicians worldwide. They predominantly affect immunocompromised hosts and are associated with a spectrum of disease. We describe a case of deep extensive gluteal muc...
Contact hypersensitivity in hand eczema – A study with Indian standard series of allergens
Patch testing is a definitive tool for diagnosing contact allergic dermatitis that provides the trends of contact sensitization in the dermatology patient community. This study was an open prospective study reporting the...
A study of theuraptic response to gentamycin on CSF of the Paediatric patients with meningitis
Introduction: Bioavailability of a drug is altered in paediatric age group especially due to many variable factors, like, larger body surface in proportion to body-wt., changes in hematocrit values and phases of maturati...
Comparison of fasting and postprandial lipid profile among patients of IHD and healthy individuals
Aim and objective: To compare fasting and post prandial lipid profile among patients of IHD and healthy individuals. Methodology: This study was conducted to assess, correlate and determine the average differential varia...