Utilization of a biochemical kit for detection of C-reactive protein (CRP) in the saliva of periodontal disease individuals
Journal Title: RSBO - Year 2011, Vol 8, Issue 3
Abstract
Introduction: Periodontal disease (PD) is a chronic inflammatory process that occurs in response to infection from bacteria in dental plaque. PD affects and destroys the periodontal tissues causing teeth loss.It is also associated to systemic diseases. C-reactive protein (CRP) is a protein produced by the liver and released into the blood during the acute phase of inflammation. Therefore, CRP is very used as a marker for inflammation process.Studies on the presence of CRP in the saliva of the subjects with PD do not exist. Objective: The aim of this study was to test a biochemical kit for CRP detection in blood plasma to monitor CRP in saliva of PD subjects. Material and methods: Saliva was collected from 40 individuals, both sexes, from 20-45 years-old, divided into two groups: Test Group – PD subjects (TG; n = 20) and Control Group (CG n = 20), without PD. The following salivary parameters were analysed: buffer capacity (BC), salivary flow (SF), pH, urea, total proteins, and CRP. Results: pH, SF and BC values were considered normal in both groups. The urea concentration was higher in TG (27.4 mg/dl ± 10.03) than CG (22.9 mg/dl ± 8.3). However, the concentration of total proteins was higher in CG (201.2 ± 100 mg/dl) than TG (155.0 ± 95 mg/dl). CRP was detected in 11 PD subjects and in eight subjects without PD. Conclusion: There were no significant differences between the two groups in relation to SF, pH and BC. However, in PD subjects’ saliva, urea values increased and total proteins decreased. The biochemical kit detected CRP in subjects’ saliva of both groups.
Authors and Affiliations
Anaila Baroni, Juliana Marchioro , Maria Torres, Paulo Tomazinho, João Brancher
Keywords
Related Articles
- EP ID EP113727
- DOI -
- Views 193
- Downloads 0
Marginal fit of metal-free crown, observed in scanning electron microscope after three years in function
Introduction: Ceramics are considered an excellent choice as esthetic restorative material, but relevant questions like marginal fit require more attention in manufacturing than conventional systems. Objective: This work...
Comparative evaluation of the accuracy of pick up transfer impressions performed with two different types of trays
Introduction: The success of implant-supported prostheses is related to the passive union between the prostheses’ connections and the implants, so it is necessary to obtain an accurate working cast. Objective: To e...
Predictability of short dental implants: a literature review
Introduction: In clinical situations where severe bone resorption has occurred following tooth loss, implant treatment options may comprise either a previous bone reconstruction or only the use of short implants. Objecti...
The use of the vinegar as a chemical auxiliary in Endodontics: a literature review
Introduction: During the root canal instrumentation with the use of files, there is the formation of a layer called “smear layer”, which may hide among other elements microorganisms capable of perpetuating an endodontic...
Criteria adopted for the toothbrush choice: a study among consumers in Florianópolis, Santa Catarina (Brazil)
Introduction and objective: To identify the criteria adopted by adult consumers when buying a toothbrush and to determine whether dentists influence on this choice. Material and methods: It was a transversal descriptive...