UTILIZATION OF BIODEGRADABLE POLYMERS FOR PERIPHERAL NERVE RECONSTRUCTION

Abstract

Peripheral nerve injuries are one of frequent cause of disability. Results of surgical procedures are not still completely satisfactory, though fast development of microsurgical technician improve their efficiency. One of the major problems in surgical treatment of the peripheral nerve injuries is ends coaptation in the case of large loss of nerve tissue. And so finding substitute implants not rejected by the organism for the recipient and providing with the success is necessary of regeneration. Recently, several synthetic nerve guide implants have been introduced and approved for clinical use to replace autologous transplants. This alternative therapy is based on pioneering studies with experimental nerve guides. This paper present a review of published studies involving biodegradable nerve guides.

Authors and Affiliations

Iwona Kardas, Wiesław Marcol, Antoni Niekraszewicz, Magdalena Kucharska, Danuta Ciechańska, Dariusz Wawro, Joanna Lewin-Kowalik, Adam Właszczuk

Keywords

Related Articles

FUNCTIONAL-TECHNOLOGICAL PROPERTIES OF MEAT-AND-VEGETABLE EMULSIONS WITH THE ADDITION OF CHITOSAN DERIVATIVES

This article provides data on the analysis of the properties of chitosan derivatives as a functional ingredient used in food technologies as a structure-forming agent, immunomodulator, enterosorbent of xantobiotics, anti...

THE ADSORPTION OF SIMVASTATIN ON CHITOSANS IN AN IN VITRO PHARMACEUTICAL MODEL

In clinical practice for the treatment of obesity, several natural macromolecular compounds are used, whose operation is based on supporting weight loss. During the use of dietary supplements containing chitosan, disease...

ROLE OF CHITOSAN OLIGOMERS IN REGULATION OF EHRLICH ASCITES TUMOR CELLS PROLIFERATION IN VITRO

Preliminary studies of proliferation of Ehrlich ascites tumor (EAT) cells and normal mammary gland epithelial cells have demonstrated the process to be inhibited by degradation products of microcrystalline chitosan, i.e....

INHIBITION OF EHRLICH ASCITES TUMOUR (EAT) CELLS PROLIFERATION THROUGH CHITOSAN-MEDIATED REGULATION OF ACTIVITY OF THE AKT PATHWAY

Isoenzyme M2 pyruvate kinase, which is a marker of cancer transformation, can take both tetramer (cytosol) and dimer (nucleus) forms. The former is responsible for ATP synthesis, and the latter demonstrates histone H1 ki...

WETTABILITY OF HYBRID CHITOSAN/PHOSPHOLIPID COATINGS

Solution spreading and Langmuir-Blodgett/Schaefer techniques were used for preparation of chitosan/phospholipid (DPPC) films on air plasma treated polyethylene terephthalate (PET) plates. The surface wetting properties w...

Download PDF file
  • EP ID EP73708
  • DOI -
  • Views 97
  • Downloads 0

How To Cite

Iwona Kardas, Wiesław Marcol, Antoni Niekraszewicz, Magdalena Kucharska, Danuta Ciechańska, Dariusz Wawro, Joanna Lewin-Kowalik, Adam Właszczuk (2010). UTILIZATION OF BIODEGRADABLE POLYMERS FOR PERIPHERAL NERVE RECONSTRUCTION. Progress on Chemistry and Application of Chitin and its Derivatives, 0(), 159-168. https://europub.co.uk/articles/-A-73708