UV Method Development and Validation of Eperisone Hydrochloride in Bulk and Tablet Formulation

Journal Title: RADS Journal of Pharmacy and Pharmaceutical Sciences - Year 2017, Vol 5, Issue 4

Abstract

Objective: To develop and validate a UV simple, precise and cost saving method for fast analysis of Eperisone Hydrochloride in Eperisone tablets. Method: The test is developed by using methanol as diluent, performed on UV visible double beam spectrophotometer at range of 200nm-400nm, and found absorbance on maximum wavelength of 260 nm. The test is then validated by using complete parameters of method validation i.e., linearity, precision, selectivity, accuracy, repeatability, robustness, limit of quantitation and detection. The complete procedure is carried out as per United State Pharmacopeia, ICH and WHO guidelines. Results: Calculate individually all parameters of method validation as per standard that should meet the validation criteria. Conclusion: As per above discussion the method is precise and accurate for analysis of Eperisone hydrochloride in Eperisone hydrochloride tablets.

Authors and Affiliations

Saima Saleem

Keywords

Related Articles

The Dilemma of Pharmacy Practice and Research in Pakistan

It is unfortunate that even after the creation of Pakistan 67 years ago, the pharmacy practice in Pakistan as a community service for the health of the people remains in infancy. Although 52 schools of pharmacy are culti...

Formulation and In-Vitro Evaluation of Polymers Blend Based Diclofenac Sodium Microparticles for Sustained Release Drug Delivery

Purpose: The purpose of research was to formulate polymeric blend based Diclofenac sodium microparticles for sustained release drug delivery. Method: The diclofenac sodium microparticles were formulated by emulsificatio...

Comparative Study of Effectiveness and Safety of Herbal Compound Medicine (Constinil) and Allopathic Medicine (Sodium Picosulfate) in Managing Constipation.

Background:This present study was conducted to observe the effectiveness and safety of the herbal compound medicine (constinil) and allopathic medicine (sodium picosulfate) in managing the constipation. The functional co...

Popularity of Soft Drinks: Colored versus Non-Colored and risks associated with their prolonged usea

Objective: The current study was conducted to evaluate the rate of consumption of cold drinks, preference of colored versus non-colored drinks among youth, effects produced by these drinks in youth and reason of consumpt...

Depression and Associated Risk Factors Among Medical and Allied Health Sciences Students of Southern Punjab, Pakistan

Aim: Depression is diagnosed mostly in medical and allied health sciences students and affects their study performance. The study was conducted to obtain the prevalence of depression of the students of a developing area....

Download PDF file
  • EP ID EP604319
  • DOI -
  • Views 200
  • Downloads 0

How To Cite

Saima Saleem (2017). UV Method Development and Validation of Eperisone Hydrochloride in Bulk and Tablet Formulation. RADS Journal of Pharmacy and Pharmaceutical Sciences, 5(4), 39-43. https://europub.co.uk/articles/-A-604319