UV-VISIBLE SPECTROPHOTOMETRIC ESTIMATION OF CURCUMIN IN NANOFORMULATION
Journal Title: International Journal of Pharmacognosy - Year 2015, Vol 2, Issue 3
Abstract
A rapid, simple, selective and precise UV-Visible spectrophotometric method has been developed for the determination of Curcumin in bulk and nano-formulation. The spectrophotometric detection was carried out at an absorption maximum of 421 nm using methanol as solvent. The method was validated for various validation parameters. The linearity range was found to be 5-25 μg/ml with a correlation coefficient of 0.9997. The accuracy was found to be within the limit. The LOD and LOQ were found to be 0.4 and 1.21 μg/ml; respectively. The results demonstrated that the method could be conveniently employed for routine quality control analysis of Curcumin in bulk and formulations.
Authors and Affiliations
Kalyan Hazra et al.
Keywords
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