VALPROATE INDUCED HYPERAMMONEMIAWITH DERANGED LIVER FUNCTION
Journal Title: Asian Journal of Pharamceutical and Clinical Research - Year 2015, Vol 8, Issue 4
Abstract
Valproate is one of the most prescribed anti-epileptic drugs. It could cause a rise in serum ammonia level in patients, especially children and youngadults. This presents with altered orientation, lethargy, focal neurological deficit, etc. If this condition is not treated, then it can be fatal. There is a goodcorrelation between fall of ammonia level and clinical improvement. We, here, present a case of valproate induced hyperammonemia and derangedliver function in a child of 1-year age admitted to a tertiary care hospital.Keywords: Hyperammonemia, Hyperammonemic encephalopathy, Valproate.
Authors and Affiliations
Ratikanta Tripathy, Jatin Kumar Majhi
Keywords
Related Articles
- EP ID EP605733
- DOI -
- Views 92
- Downloads 0
ANTIMICROBIAL AND CHITINASE INHIBITORY ACTIVITIES OF 7-BENZAMIDOCOUMARINS
Objective: The aim of this study was to examine in vitro antimicrobial activity of a series of 7-benzamidocoumarin derivatives against three Gram-positive bacteria (Bacillus subtilis, Staphylococcus aureus, and Bacillus...
CURRENT DEVELOPMENTS ON ANTI-INFLAMMATORY NATURAL MEDICINES
New anti-inflammatory substances are still vitally necessary due to intolerable side effects of the marketed anti-inflammatory drugs; however, the search for the novel entity against inflammation is challenging because o...
THE THE TERATOGENIC EFFECTS OF ETHANOLIC EXTRACT OF BINTANGUR LEAVES (CALOPHYLLUM SOULATTRI BURM. F) ON FEMALE WHITE RATS
Objectives: Drugs can cause undesired effects on the fetus during pregnancy, especially embryonic/organogenesis which could lead to defects in the fetus because some types of drugs can penetrate the placenta and will und...
SCREENING OF SOME INDIAN HOUSEHOLD SPICES FOR COMPARATIVE STUDIES OF ANTIOXIDANT AND ANTIRADICAL ACTIVITIES BY USING IN-VITRO MODELS
 Background: India is endowed with enormous varieties of spices grown in the majority of the country and one of the largest exporters of spices in theworld. Many household spices are being used integrally in the Indian...
IN VITRO STUDY OF ANTIMICROBIAL AND ANTIOXIDANT ACTIVITIES OF OXALIC ACID-DERIVED BIOACTIVE CHELATING AGENT
Objective: The aim of this study is to evaluate the biological potentials of sodium cadmium oxalate dihydrate complex prepared by a single diffusion method in the silica gel medium. Methods: The present complex was deri...