Value of bronchial wash and brush cytology in addition to histology in the diagnosis of lung cancer
Journal Title: Indian Journal of Pathology and Oncology - Year 2018, Vol 5, Issue 3
Abstract
A retrospective study was performed to evaluate the diagnostic yield of lung cancer on biopsy bronchial washings and brushings taken at fibreoptic bronchoscopy Records of 526 patients were analysed and eventually 107 patients with endobronchial lesions who had had biopsy washing and brushing were included in this study 89 cases were found to be malignant Squamous cell carcinoma was the most common malignancy Brush was found to be better than wash in tumor typing though overall tumor typing using cytology was poor Sensitivities of bronchial wash bronchial brush and biopsy were found to be 708 64 and 944 respectively Biopsy gave the only positive result in 382 only brush in 11 and only wash in 11 malignant cases Diagnostic accuracy of bronchial biopsy brush and wash was found to be 953 70 and 738 respectively Addition of bronchial wash and brush increased the positive yield by only 22 which was insignificant It was concluded that the wash and brush cytology do not significantly add to the overall yield of positive results obtained from biopsies in endobronchial lesionsKeywords Lung cancer Fibreoptic bronchoscopy Bronchial wash cytology Bronchial brush Endobronchial biopsy Diagnostic accuracy
Authors and Affiliations
Ruchee Khandelwal, Deepti Agarwal, Surbhi Bansal
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