Value of contrast-enhanced ultrasound in differentiating benign and malignant gallbladder lesions which diameter more than 1 cm
Journal Title: Journal of Surgery : Concepts & Practice - Year 2023, Vol 28, Issue 6
Abstract
[Objective] To investigate the clinical value of contrast-enhanced ultrasound (CEUS) in differential diagnosis between benign and malignant gallbladder lesions which diameter more than 1 cm. [Methods] A retrospective analysis included CEUS data of 142 cases with gallbladder lesions diameter more than 1 cm. All lesions were confirmed by surgical pathology, enhanced CT/MRI or clinical diagnosis with following up more than 2 years. To summarize the CEUS characteristics of benign and malignant gallbladder lesions over 1 cm in diameter, the CEUS characteristics of benign and malignant gallbladder lesions diameter more than 1 cm were analyzed, referring to the gallbladder CEUS guidelines. The contrast medium washout before 35 s and 60 s were used as the combined diagnosis with CEUS standard to identify gallbladder cancer, and the diagnostic efficiency was calculated respectively. [Results] There were statistical differences between the malignant group and the benign group in terms of CEUS enhancement pattern, contrast arrival time, washout time, and gallbladder wall continuity, as well as enhancement levels (P<0.001). The sensitivity, specificity, accuracy in the diagnosis of gallbladder malignant lesions were 93.0%, 83.8%, and 86.6% based on CEUS standard. The sensitivity, specificity and accuracy of diagnosis gallbladder malignant lesions were increased to 93.0%, 92.9% and 93.0% when combined with washout before 35 s of contrast medium. [Conclusions] CEUS is highly valuable in differentiating benign and malignant gallbladder lesions diameter more than 1 cm. Combined with contrast medium washout before 35 s is helpful to improve the ability of differentiating benign and malignant gallbladder lesions.
Authors and Affiliations
Meijing FENG, Xinping REN, Weiwei ZHAN, Lili ZHENG, Junjian LI
Keywords
Related Articles
- EP ID EP750930
- DOI 10.16139/j.1007-9610.2023.06.012
- Views 26
- Downloads 1
Laparoscopic radical resection of hilar cholangiocarcinoma: current status and considerations
Laparoscopic radical resection of hilar cholangiocarcinoma was complex because of the tumor near to hepatic hilum. The resection of hilar cholangiocarcinoma increased in recent years in large medical centers with safety...
How far are we from the ideal iliac vein stent
The iliac vein plays a crucial role in the reflux of venous blood from the pelvic and lower extremity regions. Due to its unique anatomical characteristics, iliac vein is susceptible to iliac vein compression syndrome (M...
Relationship between serum PD-L1 levels and prognosis of gastric cancer patients
[Objective] To analyze the serum PD-L1 levels of gastric cancer patients and its relationship with tumor stage and prognosis. [Methods] Serum of sixty patients with pathological diagnosis of gastric cancer in our hospita...
Organ preservation strategies for rectal cancer treatment: tarts or trap?
Total mesorectal excision (TME) is the standard treatment for advanced mid- and low-rectal cancer. However, the associated surgical complications and subsequent impairment of organ function limit its application. In rece...
<![CDATA[Research on standardized treatment of spontaneous rupture of hepatocellular carcinoma]]>
<![CDATA[]]>