Variation in platelet count with gestational age, weight and sex in hospitalized newborns
Journal Title: Pediatric Review: International Journal of Pediatric Research - Year 2015, Vol 2, Issue 1
Abstract
Introduction: Platelet count & CRP are diagnostic markers of neonatal sepsis. Though the platelet count remains the same throughout the neonatal period, variations in platelet count have been noted based on gestational age, weight & sex of neonates. Beside other hematological findings, changes in platelet count induced by neonatal sepsis have been the focus of many studies. Objective: To analyze the variation in platelet count with gestational age, weight and sex in hospitalized newborns. Methods: This is a retrospective case analysis of 533 neonates between January-2012 to December-2014. The parameters examined were Baseline Platelet Count, Change In Platelet Count, (Baseline Platelet Count- Change In Platelet Count)/ Baseline Platelet Count, Platelet Nadir, Incidence, Duration & Severity of Thrombocytopenia. Statistical Analysis: All data were collected in validated preformatted proforma sheet & analysed using appropriate statistical methods. Results: 533 babies were studied. About 21.2% had Culture negative sepsis, 9.75% had culture positive sepsis & 69.04% had no sepsis. No difference in any platelet parameter was noted between female & male babies. The prevalence of early onset sepsis in our study was 17.44% & late onset sepsis was 13.50%. Significant variations of all platelet indices were noted among lower gestational age babies. Significant variations in the Incidence, Prevalence & duration of thrombocytopenia were noted depending on the weight of the baby. Conclusion: The baseline platelet count of the neonates remains uniform irrespective of sex, weight or gestational age. There are quantitative differences in the platelet response based on weight and gestational age
Authors and Affiliations
Rabindran Rabindran, Hemant Parakh, Ramesh J K, Prashant Reddy
Keywords
Related Articles
- EP ID EP322377
- DOI 10.17511/ijpr.2015.1.001
- Views 129
- Downloads 0
Patent ductus arteriosus – clinical profile and outcome after treatment in a tertiary care hospital
Background: Patent ductus arteriosus (PDA) is the commonest congenital heart disease seen in neonatal ICU. Methods: A prospective observational study was conducted in the neonatal intensive care unit of Vydehi institute...
Minocycline trial in japanese encephalitis: a double blind, randomized placebo study
Objective: To evaluate the effect of minocycline in Japanese Encephalitis (JE ) patient on reduction in mortality, neurological deficit and behavioral outcome. Design: Double blind randomized placebo control trial. Setti...
Roux-en-Y hepaticojejunostomy versus hepaticoduodenostomy after excision of choledochal cyst: A randomized clinical trial and experience in a tertiary care hospital
Introduction: Excision of choledochal cyst is required to relieve biliary obstruction thereby protecting the liver and pancreas as well as to prevent malignancy in long term. But controversy persists in the two existing...
A prospective seroepidemiologic study on dengue in children in Southeastern Rajasthan, India
Background: In India, dengue epidemics are becoming more frequent (WHO, 2008). The majority of dengue viral infections are self-limiting, but complications may cause high morbidity and mortality. Objectives: To assess th...
Acute hepatic failure with encephalopathy in children
Introduction: Hepatic encephalopathy is a serious and likely to be reversible neurophyschiatric state in the patient of liver failure. Acute hepatic failure is a life-threatening condition in children. Objectives: The st...