VARIATION IN THE YAK CALPASTATIN GENE (CAST)
Journal Title: International Journal of Genetics - Year 2012, Vol 4, Issue 1
Abstract
Calpastatin (CAST) is a specific inhibitor of calpain (calcium-dependent cysteine protease). This study investigated the potential for variation in yak (Bos grennies) CAST. PCR-SSCP analysis of exon 6 of yak CAST revealed three unique patterns (named A-C). Sequencing of the amplicons revealed two nucleotide substitutions. One substitution (c.398G/C) would nominally change the amino acid sequence (p.S133T) of yak calpastatin. The variant sequence A which carried c.398C was the most common in the yaks tested (95.1%). This is the first report that found yak CAST is variable, and as in pigs, sheep and cattle, this variation may affect animal production traits.
Authors and Affiliations
J. G. H. HICKFORD, G. YANG, H. ZHOU, J. HU, Y. LUO
Keywords
Related Articles
- EP ID EP170127
- DOI 10.9735/0975-2862.4.1.72-73
- Views 76
- Downloads 0
GENERATION MEAN ANALYSIS FOR MORPHO-PHENOLOGICAL TRAITS IN BREAD WHEAT (Triticum aestivum L.)
The study was carried to investigate the inheritance of gene action for various morpho-phenological traits in bread wheat at the Haryana Agricultural University, Hisar during rabi 2013-14 and 2014-15. A set of six genera...
MOLECULAR ANALYSIS OF BLAST RESISTANCE GENES IN RICE USING GENE LINKED AND GENE BASED MARKERS
Rice blast caused by Magnaporthe oryzae, spread in more than 85 countries and has caused great yield loss. Development and growing of rice varieties would be the most effective way to control blast disease. Molecular ana...
METAGENOMICS ANALYSIS OF EUKARYOTIC COMMUNITY IN SOIL USING 18S AND 28S rRNA GENE HIGH THROUGHPUT SEQUENCING
The present study applied metagenomics to characterize the diversity and relative occurrence of eukaryotic organisms in the soils of Chandan plant (Santalum album; MS1) and Bamboo plant (Bambussa bambus; MS2). DNA-based...
CHROMOSOMAL Q-HETEROCHROMATIN POLYMORPHISMS IN 3 ETHNIC GROUPS (KAZAKHS, RUSSIANS AND UYGHURS) OF KAZAKHSTAN
A comparative study of polymorphic variants of chromosomal Q-heterochromatin regions (Q-HRs) was performed in three ethnic groups (Kazakhs, Russians, and Uyghurs) of Kazakhstan. The number of chromosomal Q-HRs in the gen...
HETEROSIS STUDIES FOR GRAIN YIELD AND ITS RELATED CHARACTERS IN MUNGBEAN (Vigna radiata L. Wilczek)
A study was conducted in mungbean (Vigna radiata L.) at Department of Genetics and Plant Breeding, C. P. College of Agriculture, Sardarkrushinagar Dantiwada Agricultural University, Sardarkrushinagar (Gujarat) to assess...