Variation of Certain Haemostatic Parameters in Hypothyroidism

Journal Title: Journal of Medical Science And clinical Research - Year 2017, Vol 5, Issue 8

Abstract

Thyroid disorders which has increased incidence in females, were found to effect coagulationfibrinolytic system. In the present study an effort is made to evaluate the alterations of certain haemostatic parameters in overt hypothyroid patients. Bleeding time, clotting time & platelet count were estimated in hypothyroid subjects and control group, with sample size of 15 each. Hypothyroid group included subjects with low FT3, FT4 & elevated TSH value (mean 14.9 mU/L).Both the groups were age and sex matched. The results showed prolonged bleeding time and clotting time which were statistically significant with p-value of <0.0001 for both the parameters each. In the present study, hypothyroid group showed decreased platelet count when compared to control group which was statistically significant with a p-value of <0.0001.This finding was in contrast to many of the previous studies which showed either increase in platelet count or even if there was decrease, it was statistically not so significant. This shows increased bleeding tendency or hypocoagulable state in overt hypothyroid patients. The more elevated the TSH levels, the more the deviation of haemostatic parameters from normal.

Authors and Affiliations

Dr Lanke Vani

Keywords

Related Articles

Clinical Study of Complications of Laparoscopic Cholecystectomy and Open Cholecystectomy

This is clinical study of 440 patients undergoing elective laparoscopic and open cholecystectomy in a tertiary care hospital during the period from June 2013 to June 2016. Out of the 440 patients, 50% underwent laparosco...

Dexmedetomidine Versus Nitroglycerine for Controlled Hypotension in Head & Neck Surgery: A Prospective Randomised Clinical Study

Aim: Present study is aimed to compare Dexmedetomidine with Nitroglycerine for controlled hypotension in head & neck surgeries in terms of intra-operative blood loss, clearity of surgical field, haemodynamic parameters,...

Expect the Worse-A Case of Unexpected Death of A Eight Year Old Boy Due to Invasive Pneumococcal Infection

Streptococcus pneumoniae is an important pathogen that kills more than 1 million children each year worldwide. Childhood pneumococcal disease is a major cause of life threatening pneumonia, bacteremia and meningitis1 . I...

A Rare Case of Fournier’s Gangrene of Female with type 2 Diabetes Mellitus

Fournier’s gangrene is relatively uncommon condition, especially in female patients. The literature suggests that Fournier’s gangrene in women may arise from vulvar or Bartholin’s gland abscesses or may result from hyste...

Chemical analysis of gallstones and quantitative analysis of its biochemical components viz total cholesterol, total bilirubin, calcium and inorganic phosphate

To understand gallstone disease, the knowledge of it’s chemical composition becomes very important. In our study, we have done the quantitative chemical analysis of gallstones collected from 40 patients and have classifi...

Download PDF file
  • EP ID EP529155
  • DOI -
  • Views 91
  • Downloads 0

How To Cite

Dr Lanke Vani (2017). Variation of Certain Haemostatic Parameters in Hypothyroidism. Journal of Medical Science And clinical Research, 5(8), 26966-26971. https://europub.co.uk/articles/-A-529155