Varied Histopathology Of Sertoli Cell Tumors-A Diagnostic Dilemma
Journal Title: National Journal of Medical and Dental Research - Year 2017, Vol 5, Issue 3
Abstract
Introduction:Ovarian Sertoli-Leydig cell tumors (STLC) also known as androblastoma, belong to the sex cord-stro¬mal tumors which resemble a testicular pattern of differentiation. Ovarian Sertoli-Leydig cell tumors account for less than 1% of all primary ovarian tumors and occur in young women as unilateral well ,intermediate or poorly differentiated ovarian mass or as masses with heterologous elements. AIM:The aim of the present study was to evaluate various histological patterns of 14 cases of Ovarian sex cord stromal tumor specifically sertoli cell tumor in patients visiting the Gynaecology OPD of Eras Lucknow Medical college and Hospital. Methodology:In the present study, we analyzed the clinical data from 14 patients, who were diagnosed as patients with ovarian Sertoli-Leydig cell tumors and treated in the Obstetrics and Gynecology Hospital of Eras Lucknow Medical College and Hospital. We collected the data over a period of one year from June 2015-June 2016. Clinical data, including age, date of initial diagnosis, presenting symptoms and signs, type of surgery, stage at presentation, histological type, menstrual functions, and fertility of all patients were collected from patient medical records and retrospectively reviewed. Results: We found that out of the 14 cases 3 were well differentiated ,2 were moderately differentiated and 8 were poorly differentiated with each tumor showing 11 patterns of poor differentiation. Conclusion: STLC is a rare predominantly unilateral gonadal tumor belonging to the sex cord-stromal type. A thorough knowledge of its differentials as well as its grading and staging is required for optimal treatment of the tumor.
Authors and Affiliations
Parul Gupta, Neema Tiwari, Nirupma lal, Aamir Hussain, HP Gupta
Keywords
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