Ventilator associated pneumonia (VAP) in an intensive care unit of a tertiary care hospital: incidence, their microbial etiology, risk factors and role of multidrug resistant pathogens
Journal Title: IJAR-Indian Journal of Applied Research - Year 2017, Vol 7, Issue 2
Abstract
VAP is serious nosocomial infection and is associated with multi-drug resistant organisms studied. e aim of study is to find the incidence, microbial causes, antibiotic susceptibility pattern and the incidence of multidrug resistant organisms associated of VAP in mechanically ventilated patients in intensive care units of a tertiary care hospital. Patients and Methods: In this study, a prospective study of 50 patients with VAP between January 2016 and December 2016 was performed based on age, gender, underlying illness, duration of hospitalization and mechanical ventilation, prior antibiotic treatment were obtained . Result: 6 (12%) were diagnosed to have VAP of which, 2(33.3%) patients developed early onset and 4(66.6%) have late onset VAP. VAP was polymicrobial in 2 (33.3%) patients and monobacterial in 4(66.6%) cases. , Klebsiella pneumoniae was the most common organism associated with VAP. Out of 7 gram negative organisms, 6(85.7%) were multidrug resistant and ESBL producers. Mortality rate in VAP patients 50% and in neonates 100%. Risk factor found in VAP cases were increased duration mechanical ventilation, prior antibiotic therapy in adults and in neonates was low birth weight. Conclusions: VAP is increasingly found to be associated with multi-drug resistant organisms that explain the high rate of colonization due to these pathogens. Etiological agents also vary based on type of ICU and patient studied. Therefore knowing the susceptibility pattern of local microbial isolates guide the clinician to choose the appropriate empirical therapy followed by de-escalation strategy focused on narrow spectrum antibiotics after the culture and sensitivity report.
Authors and Affiliations
Prashant V. Male, Manish kumar Kashyap, Riddhi Ajay Bora, Vinayak V. Kshirsagar
Keywords
Related Articles
- EP ID EP461655
- DOI -
- Views 29
- Downloads 0
A STUDY OF INTERNAL ASSESSMENT OF POST GRADUATE STUDENTS WITH MANAGEMENT AND GENDER
Today the year-end external examination is the sale basis of assigning marks which in term serve as the basis on which the rewards of the University and ultimately the prizes of the society are awarded. The students' aca...
A Study of Transcerebellar Diameter in Foetus as an Additional Marker for Estimation of Gestational Age
Gestational age in pregnant women with known last menstrual period is commonly assessed by ultrasonographic examination using parameters like biparietal diameter (BPD), head circumference (HC), abdominal circumference (A...
Glycosylated hemoglobin (HbA1c): A Biomarker of Anti Aging
Glycosylated hemoglobin (HbA1c) is a marker of evaluation of long-term glycemic control in diabetic- pa tients that predict risks for the development and progression of diabetic complications. The aim of this study is to...
Japan’s Recent Initiatives and Evolving Role in The Palestine
Palestine peace process is a core issue in contemporary Middle East region. Japan imports more than 80 percent of its crude oil from the Gulf Cooperation Council and stability in the Middle East is of great interest and...
An Observational Study to Find Out the Available Pediatric Radiology Apps for Smart Phones.
The observational study was conducted to find out the available Pediatric Radiology Apps for the Smart phones. Both Apple & Google play stores were searched using predefined search key phrases Pediatric Radiology, Pe- di...