Ventilator associated pneumonia (VAP) in an intensive care unit of a tertiary care hospital: incidence, their microbial etiology, risk factors and role of multidrug resistant pathogens
Journal Title: IJAR-Indian Journal of Applied Research - Year 2017, Vol 7, Issue 2
Abstract
VAP is serious nosocomial infection and is associated with multi-drug resistant organisms studied. e aim of study is to find the incidence, microbial causes, antibiotic susceptibility pattern and the incidence of multidrug resistant organisms associated of VAP in mechanically ventilated patients in intensive care units of a tertiary care hospital. Patients and Methods: In this study, a prospective study of 50 patients with VAP between January 2016 and December 2016 was performed based on age, gender, underlying illness, duration of hospitalization and mechanical ventilation, prior antibiotic treatment were obtained . Result: 6 (12%) were diagnosed to have VAP of which, 2(33.3%) patients developed early onset and 4(66.6%) have late onset VAP. VAP was polymicrobial in 2 (33.3%) patients and monobacterial in 4(66.6%) cases. , Klebsiella pneumoniae was the most common organism associated with VAP. Out of 7 gram negative organisms, 6(85.7%) were multidrug resistant and ESBL producers. Mortality rate in VAP patients 50% and in neonates 100%. Risk factor found in VAP cases were increased duration mechanical ventilation, prior antibiotic therapy in adults and in neonates was low birth weight. Conclusions: VAP is increasingly found to be associated with multi-drug resistant organisms that explain the high rate of colonization due to these pathogens. Etiological agents also vary based on type of ICU and patient studied. Therefore knowing the susceptibility pattern of local microbial isolates guide the clinician to choose the appropriate empirical therapy followed by de-escalation strategy focused on narrow spectrum antibiotics after the culture and sensitivity report.
Authors and Affiliations
Prashant V. Male, Manish kumar Kashyap, Riddhi Ajay Bora, Vinayak V. Kshirsagar
Keywords
Related Articles
- EP ID EP461655
- DOI -
- Views 50
- Downloads 0
A STUDY OF THE BURDEN OF CARE AND THE NEEDS OF CAREGIVERS OF PATIENTS WITH SCHIZOPHRENIA
Background: There were very few Indian studies regarding caregiver burden and needs of caregivers in patients of schizophrenia. Methodology: The study evaluated socio-demographic data, caregiver burden, caregiver needs a...
INTRATHECAL FENTANYL VERSUS DEXMEDETOMIDINE AS ADJUVANTS TO HYPERBARIC BUPIVACAINE IN INFRAUMBILICAL SURGERIES
The study evaluated and compared the efficacy of intrathecal fentanyl 25μg and dexmedetomidine 5μg with 0.5% hyperbaric bupivacaine. Each study group consisted of 25 patients. Patients were randomly divided to receive in...
A study of Adolescents in relation to Aggression across high and low Social Intelligence
Present study was conducted to find out the relationship between aggression and social intelligence among adolescents. The study was carried out under descriptive method of research with a sample of 200 school going adol...
A STUDY TO ASSESS THE EFFECTIVENESS OF STRUCTURED TEACHING PROGRAMME ON KNOWLEDGE REGARDING HAZARDS OF BEVERAGES TOXICITY AMONG STUDENTS IN A SELECTED NURSING COLLEGE AT CHENNAI
A study to assess the effectiveness of structured teaching programme on knowledge regarding hazards of beverages toxicity among students in a selected Nursing college at Chennai. The pre experimental research design was...
BRAINSTEM EVOKED RESPONSE AUDIOMETRY AND ITS APPLICATION IN HEARING LOSS ASSESMENT IN CHILDRENS.
BERA is a non invasive technique, easily recordable, not affected by sedation, anesthesia or age which helps in hearing assessment. Approximately 1 of every 1000 children is born deaf. Early diagnosis of hearing impairme...