Ventricular Septal Defect: Peculiarities of Early Neonatal and Postnatal Diagnosis, Clinical Manifestations, Treatment and Prognosis at the Contemporary Stage

Journal Title: Здоров`я дитини - Year 2016, Vol 4, Issue 72

Abstract

The article presents the literature data on the incidence, the main clinical manifestations, modern methods for early neonatal and postnatal diagnosis and treatment of ventricular septal defect in children, as well as the prognosis of this disease. According to the International Classification of Diseases, 10th revision, ventricular septal defect is classified as Q21.0 Ventricular septal defect. Incidence. In the overall structure of congenital malformations of the cardiovascular system, ventricular septal defect has about 20 %. Diagnosis. Moderate ventricular septal defect is manifested by shortness of breath, rapid fatigability during feeding, delay in physical development. Significant arterial-venous shunt in the first month of life is accompanied by a transient mild cyanosis when the baby is fed and cries. Infants develop high pulmonary hypertension, circulatory failure, malnutrition. Small noise intensity is typical for newborns in the first weeks or even months of life, which is due to physiologically increased intravascular pulmonary resistance. Systolic murmur is extended to the entire systole with maximum amplitude at the left edge of the sternum at the level of III–IV intercostal spaces. Sclerotic phase of pulmonary hypertension with ventricular septal defect is defined as Eisenmenger reaction. The clinical picture of this disorder depends on the degree of hemodynamic instability caused by the defect parameters, the pressure level in the pulmonary artery, vascular pulmonary resistance, the magnitude and direction of the shunt through the defect. Diagnosis is confirmed by characteristic changes in the electrocardiogram, echocardiography and chest radiograph. Treatment. Small muscular ventricular septal defects often close spontaneously during the first 2 years of life. Drug correction is needed in the development of congestive heart failure. The optimum age for surgery — 5–9 years.

Authors and Affiliations

K. A. Kalashnikova, N. O. Nikitina

Keywords

Related Articles

Improving the Efficiency of Treatment of Children with Cystic Fibrosis by Including Pulmozyme to Standard Therapy

The efficiency of treatment of 12 children with cystic fibrosis using Pulmozyme on a background of standard therapy during a year has been analyzed. In comparison with the treatment of 20 patients with cystic fibrosis, w...

Biochemical Description of the Systemic Inflammatory Response in infants after Severe Birth Asphyxia

This article presents the results of a study of biochemical indicators of systemic inflammatory response in infants after severe birth asphyxia. In a group of 34 newborns there were determined the indicators of inflammat...

Asymptomatic Hyperamylasemia in the Onset of Inflammatory Bowel Diseases in Children: A Case Report

The article analyzed the literature data on the epidemiology, etiology, mechanisms of pancreatic lesions in inflammatory bowel diseases in children. Range of pathological conditions of the pancreas in patients with infla...

State of Microbiocenosis and Intestinal Local Immunity in Healthy Infants: Results of a Study

State of intestinal microbiocenosis is one of the key components of the process of formation of health in children. According to the findings of a survey conducted in IPOG of NAMS of Ukraine, up to 60 % of young children...

Predicting the risk of chronic bronchitis in teenage smokers

Background. The purpose of the study was to create a prognostic model of the risk of chronic respiratory pathology in teenage smokers comfortable to use in practical medicine. Materials and methods. 73 teenage smokers ag...

Download PDF file
  • EP ID EP192002
  • DOI -
  • Views 79
  • Downloads 0

How To Cite

K. A. Kalashnikova, N. O. Nikitina (2016). Ventricular Septal Defect: Peculiarities of Early Neonatal and Postnatal Diagnosis, Clinical Manifestations, Treatment and Prognosis at the Contemporary Stage. Здоров`я дитини, 4(72), 71-75. https://europub.co.uk/articles/-A-192002