VISUAL SCREENING WITH ACETIC ACID AND LUGOL’S IODINE- A BETTER OPTION FOR EARLY DETECTION OF CERVICAL INTRAEPITHELIAL NEOPLASIA
Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2018, Vol 7, Issue 6
Abstract
BACKGROUND Visual inspection based screening tests such as visual inspection with dilute acetic acid 4% (VIA) and with Lugol’s iodine- VILI have been proposed as alternatives to cytology in mass screening program. To date there is only limited information on the accuracy of these tests in detecting high-grade squamous intraepithelial lesions (HSIL). MATERIALS AND METHODS This is a descriptive study done in Mahatma Gandhi Medical College and Hospital from July 2014 to June 2016. Total no. of women screened were 4405. Out of them 14% were positive on VIA, 16.2% were positive on VILI and 12 were diagnosed with HSIL. Sensitivity, specificity, positive and negative predictive values for VIA were 94.1%, 86.0%, 2.5% and 99.9% and sensitivity, specificity, positive and negative predictive values for VILI were sensitivity 82.3%, specificity 84%, PPV 2.0% and NPV 99.9%. Both VIA and VILI had a significant higher sensitivity and specificity. Both tests were accurate visual tests for use in screening and treatment programme in low resource settings. RESULTS This study was carried out during July 2014 to June 2016. A total of 4405 women were screened. Out of 4405 women, 14% were VIA positive and 16.2% were VILI positive. Out of VIA positive, Biopsy was taken. Out of VIA positive 83% were normal, 39 had low-grade lesion i.e. 6.9% and 16 had HSIL i.e. 2.5%. In VILI positive women, 36 had low-grade lesion and 11 had HSIL and 3 were having invasive carcinoma. CONCLUSION Sensitivity, specificity, positive and negative predictive values for VIA were 94.1%, 86.0%, 2.5% and 99.9% and sensitivity, specificity, positive and negative predictive values for VILI were sensitivity 82.3%, specificity 84%, PPV 2.0% and NPV 99.9%. Both VIA and VILI had a significant higher sensitivity and specificity. Both tests are accurate visual tests for use in screening and treatment programme in low resource settings.
Authors and Affiliations
Naruka Nisha, Jain Monika, Chakraborty Saptrishi, Mathur Abha
Keywords
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- EP ID EP399017
- DOI 10.14260/jemds/2018/173
- Views 95
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