Vitamin D Intoxication: Consequence of Misconception - A Case Report
Journal Title: International Journal of Contemporary Medical Research - Year 2018, Vol 5, Issue 8
Abstract
Introduction: Among 4 fat soluble vitamins vitamin D is considered as wonder drug as number of studies showed its deficiency is associated with cardiovascular diseases, metabolic diseases, abdominal obesity, hyperglycemia, asthma etc., but on the other hand unsupervised, inadvertent use of vit D also leads to its toxicity. Case Report: An 11 years and 6 months old girl was presented with 15days history of burning abdominal pain mainly in epigastric region, constipation, decreased appetite followed by several episodes of vomiting. There was history of administration of total 12 doses of intramuscular injection of Vitamin D (600,000IU/dose) for improvement of her height following which features of Vitamin D intoxication manifested. On examination her height was below 3rd centile (though her height velocity was within target range) and blood pressure was above 99th centile, no other significant finding was there on systemic examination. On laboratory studies renal function tests were deranged, hypercalcemia, increased level of serum 25-hydroxy D, decreased serum parathormone (PTH), GFR were noted. USG abdomen, fundus examination reports were normal. Hydration therapy, oral diuretic, oral bisphosphonate therapy were started. Symptomatic improvements was noted after 48hours, and blood pressure, laboratory parameters came to within normal level over next 2 weeks. Conclusion: Due to awareness of vit D deficiency the common practice of overzealous vit D supplementation should be avoided to prevent the consequences of its toxicities. Vit D3 metabolic profiling and safety parameters must be evaluated before initiation of therapy.
Authors and Affiliations
Aditi Das, Shaad Abqari, Kamran Afzal
Keywords
Related Articles
- EP ID EP431734
- DOI -
- Views 117
- Downloads 0
Assessment of Diabetic Retinopathy by Fluorescein Angiography
Introduction: Diabetic retinopathy is one of the leading causes of blindness. According to “Statistics on blindness in the Model Reporting Area 1969-70, diabetic retinopathy was responsible for 11.1% of new cases of lega...
Endoscopic Dacryocystorhinostomy: Our Experience
Introduction: Dacryocystorhinostomy is a surgical procedure for epiphora caused by obstruction of the nasolacrimal duct. Either an external or endonasal surgical approach can be used for dacryocystorhinostomy. Study Obje...
Evaluation of Recombinant Human Platelet Derived Growth Factor- BB in Healing of Chronic Diabetic Foot Ulcers
Introduction: Diabetic foot problems are common throughout the world resulting in major economic consequences. Once a wound developed in diabetics it remains open for prolonged periods. Senescent and altered resident cel...
Aerobic Bacterial Profile of Diabetic foot and its Antibiogram in RIMS, Ranchi - a Tertiary Care Hospital
Introduction: Diabetic foot is the most serious complications of diabetes. Hyperglycemia impairs body defense mechanism, leads to increase infection rate. Thus for proper management it is necessary to know about most eff...
Linear Nevus Sebaceous with Vitamin D3 Resistant Rickets (Schimmelpenning Syndrome)
Introduction: Schimmelpenning syndrome is a neurocutaenous condition characterized by one or more sebaceous nevi, usually on the face or scalp, associated with anomalies of the central nervous system, ocular system, skel...