Vitamin D Status and Glycemic Control in Type 2 Diabetes Mellitus
Journal Title: Journal of Medical Science And clinical Research - Year 2017, Vol 5, Issue 10
Abstract
India has widespread prevalence of diabetes and hypovitaminosis D. This study was conducted to evaluate the relationship between serum 25-hydroxyvitamin D [25(OH)D] and glycemic control in patients with type 2 Diabetes Mellitus [T2DM]. 157 subjects (100 T2DM; 57 controls) were sampled and their 25(OH)D, FBG, PPBG and HbA1c were measured. Additionally, T2DM patients were classified into controlled diabetic and uncontrolled diabetic group based on glycemic control (HbA1c level <7% or ≥ 7%). Data analysis was done by t-test for continuous measures and chi-square test for categorical measures. Mean vitamin D level was significantly lower in the diabetic compared to Control group (15.1 ± 5.18 v/s 22.66 ± 5.49 ng/ml, P<0.01). 82% diabetics and 33.4% controls were Vitamin D “deficient” (<20ng/ml). 18% diabetics and 56.1% Controls were Vitamin D “insufficient” (20-29 ng/ml). FBS (96.8±16.3 v/s 146.5±55.2, P<0.01), PPBS (125.3±22.9 v/s 210.5±76.6, P<0.01), HbA1c (8.1 ± 2.2 % v/s 5.6 ± 0.2 %, P<0.01) and calcium (9.21±.89 v/s 7.89±.70, P =0.04) were also found to be statistically different between controls and diabetics. Mean vitamin D level in the controlled diabetic v/s uncontrolled diabetic group was (14.95±4.77 v/s 15.15±5.59 ng/ml, P =1.00). Thus, Vitamin D deficiency may be an etiological factor for the development of T2DM, but may not have a role in the glycemic control in T2DM.
Authors and Affiliations
Fahmiya Leena Yacoob
Keywords
Related Articles
- EP ID EP529718
- DOI -
- Views 93
- Downloads 0
Anaemia in Pregnancy a Prospective Observational Study in Tertiary Care teaching hospital of North India
The aim of this study is to find prevalence of anaemia in specified population in north India and to know various adverse outcomes of anaemia in mother and child. Methods: A prospective observational study done in pregna...
Obstetric Outcome Following Vesicular Mole Evacuation in a Tertiary Care Centre
Background: Gestational Trophoblastic Diseases (GTD) are a group of diseases in which the basic disorder lies in the abnormal development and growth of trophoblast. The success story of the GTD is the curability by chemo...
Delayed Presentation of Aspirated Foreign Body with Peculiar Symptoms
Aspiration of foreign body is a common problem in children but rarely seen in adults also. They present to the hospital as emergency and on most occasions are removed bronchoscopically. Some late presentation of aspirate...
Cystic Lymphangioma – Report of Atypical Case in Adult Female
Lymphangioma are uncommon lesion of lymphatic channels that are often present at birth and diagnosed mostly (90%) before the age of two years. lymphangiomas are mainly seen in neck. We report a case of cystic lymphangiom...
Dietary Management Practiced By Subjects Suffering From Chronic Disorders
Health is a basic pre-condition for happiness and progress in life of an individual and quality health care is lifeline for the growth of any nation. The metabolic disorders we know today is increasing day by day due to...