Wilms' Tumor in Children: An Experience of SIOP Protocol from Tertiary Centre
Journal Title: Journal of Medical Science And clinical Research - Year 2015, Vol 3, Issue 9
Abstract
Background: Wilms’ tumor is the commonest renal .tumor. Survival depends on stage and biologic behavior and economic settings. International Society of Pediatric Oncology (SIOP) has laid down protocol for developing country. Methods: Prospective observational study. aged 1-12 year with wilms’ tumor department of Pediatrics IPGMER, Kolkata .from February 2009- August 2012.. All cases are managed according to SIOP 2001protocol. Follow-up for 2 to 4 years Prognosis is noted in terms of local recurrence or metastasis and overall survival. Results: Out of 8 children male 5 and female 3with age of presentation ranging from 3-12 year (median-5 year). Abdominal lump is the main clinical presentation along with hematuria in 2 and hypertension in 1 child. Clinically and histologically 6 of the children was on stage 1 and 2 were on stage 2. . Out of 8 children, 1 child died soon after nephrectomy due to postoperative complications. Remaining 7 children are disease free till date with no evidence of local recurrence or metastasis. Conclusions: SIOP protocol can be used in management of pediatric Wilms' tumor Stage I and II with excellent prognosis in our settings. However more studies are needed to bring SIOP protocol in treatment of Wilms tumor in India or develop own protocol for our country.
Authors and Affiliations
Anirban Chatterjee
Keywords
Related Articles
- EP ID EP212347
- DOI -
- Views 74
- Downloads 0
Status of Threatened Medicinal Plants in tropical Forest of Malyagiri Hill Ranges, Odisha, India
Malyagiri hill ranges located on the south of Pallahara town of Angul district in the state of Odisha is endowed with rich flora and fauna. This area is rich with large no. of medicinal plants and plants of other socio-e...
Antibiotic Profiles of Bacterial Enteropathogens associated with Diarrhea among HIV Positive and Negative Patients aged below five years in Western Kenya
Background: The progressive increase in antibiotic resistance among enteric pathogens, particularly in developing countries, is an issue of special concern and it is believed that bacterial enteropathogens in AIDS patien...
Presenting A Case of Supra Renal Mass in Young Child - A Case Report
Abstract
Acute Subdural Hematoma in the Post Partum Period – A Case Report
Acute neurological syndromes are occasionally reported during pregnancy and in the postpartum period. They include preeclampsia, eclampsia, haemorrhagic or ischaemic stroke, cerebral sinus venus thrombosis, posterior rev...
Incidence and Clinical Presentation of Male Breast Cancer at Regional Cancer Center of India
Background: Breast cancer in male is a rare malignancy with an incidence of less than 1% of all breast cancer. It is commonly seen in elderly men of 60 to 70 years. Most the patients present with advanced stage and progn...