Functional characterization of the UBIAD1 protein: The nodal point for vitamin K and cholesterol synthesis. From corneal dystrophies to lifestyle diseases

UbiA prenyltransferase domain-containing protein 1 (UBIAD1) is a transmembrane enzyme that plays an essential physiological role in the human body. The most important functions of the UBIAD1 protein include (i) the synth...

Zastosowanie wysokich dawek tokoferolu w prewencji i potencjalizacji działania dioksyn w doświadczalnym zapaleniu

Emisja do środowiska toksycznych i stabilnych substancji chloroorganicznych, z których jedną z ważniejszych grup są dioksyny, stanowi istotny problem ekologiczny i zdrowotny. Polichlorowane dibenzodioksyny (PCDD), okre...

Zaburzenia immunologiczne w sepsie oraz ich leczenie jako istotny problem współczesnej intensywnej terapii

The role of genetic (PON1 polymorphism) and environmental factors, especially physical activity, in antioxidant function of paraoxonase*

Paraoxonase 1 ([i]PON1[/i]) is a member of a three-gene family ([i]PON1, PON2[/i], and [i]PON3[/i]). PON1 activity dominates in human plasma. It is secreted from hepatic cells and is found in the circulation bound to hig...

The biological and pharmacological activity of essential oils in the treatment and prevention of infectious diseases

Despite the large progress in medicine and pharmacy in the last few decades, traditional treatment of bacterial or viral diseases is frequently ineffective and is connected with some side effects. Currently, there is obs...