Wykorzystanie technik UV-Vis oraz IR dla celów identyfikacji leków w porowatych nośnikach
Journal Title: CHEMIK nauka-technika-rynek - Year 2011, Vol 65, Issue 7
Abstract
W ostatnim czasie jako obiecujące nośniki substancji biologiczno czynnych rozważane są materiały porowate. W pracy przedstawiono krzemianowe struktury typu SBA-15 modyfikowane niobem oraz grupami organicznymi jako potencjalne nośniki leku - ibuprofenu. Omówiono zastosowanie metod spektroskopii FT-IR oraz UV-Vis ciała stałego dla potwierdzenia obecność leku w materiale. Dodatkowo poprzez spektrofotometryczny pomiar zawartości leku w buforze opracowany został profil uwalniania ibuprofenu z nośnika, w określonych odstępach czasu.
Authors and Affiliations
Katarzyna Walczak-Zeidler, Izabela Nowak
Keywords
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