Revista Científica Facultad de Ciencias Químicas y Farmacia

Revista Científica Facultad de Ciencias Químicas y Farmacia

Basic info

  • Publisher: Universidad de San Carlos de Guatemala
  • Country of publisher: guatemala
  • Date added to EuroPub: 2019/Jul/16

Subject and more

  • LCC Subject Category: Biological Sciences
  • Publisher's keywords: Biological Sciences, Pharmacy, Chemistry
  • Language of fulltext: spanish, catalan

Publication charges

  • Article Processing Charges (APCs): No
  • Submission charges: No
  • Waiver policy for charges? No

Editorial information

Open access & licensing

  • Type of License: CC BY-NC-SA
  • License terms
  • Open Access Statement: Yes
  • Year open access content began: 2012
  • Does the author retain unrestricted copyright? False
  • Does the author retain publishing rights? False

Best practice polices

  • Permanent article identifier: DOI
  • Content digitally archived in: Nopolicy
  • Deposit policy registered in: None

This journal has '5' articles

Perfil metabólico de estudiantes de medicina antes y después de turno en los hospitales Roosevelt, San Juan de Dios, Regional de Cuilapa, Regional de Escuintla y Nacional de Antigua

Perfil metabólico de estudiantes de medicina antes y después de turno en los hospitales Roosevelt, San Juan de Dios, Regional de Cuilapa, Regional de Escuintla y Nacional de Antigua

Authors: Castillo-Ochoa, Oscar; Pinto-Zelada, María; Beza-González, Cathleen; Martínez-Ortiz, Samuel; López Rodriguez, María; Menéndez-Salguero, Rita; Marroquí...
( 1 downloads)
Abstract

The long work shifts of 16 to 24 hours and up to 32 to 36 hours that doctors have in the hospitals, exert a negative effect on their physical and emotional health. Alterations have been described in the levels of glycaemia, catecholamines, cortisol, heart rate, among others. This research aimed to compare the metabolic profile of internal and external medical students of the Faculty of Medical Sciences of the University of San Carlos of Guatemala, before and after their hospital shifts. This paired study was carried out in many national hospitals, such as: Hospital Nacional Roosevelt, Hospital General San Juan de Dios, Hospital Regional de Cuilapa, Hospital Regional de Escuintla, and Hospital Nacional de Antigua. Glycaemia, lipid profile and cortisol, vital signs and lifestyles before and after each shift were evaluated in 80 students. Significant variation was observed in cortisol values (p = .023), glycemia (p = .002) and triglycerides (p = .050) before and after the work shift. After the work shift the students experienced an increase in cortisol values and a decrease in glycaemia and triglyceride levels. These changes were associated to the different hospitals

Keywords: hydrocortisone, physiological stress, blood glucose, Medical students
Thrombocytopenia versus SOFA to predict mortality in patients with sepsis in the Intensive Care Unit of a tertiary hospital in Guatemala

Thrombocytopenia versus SOFA to predict mortality in patients with sepsis in the Intensive Care Unit of a tertiary hospital in Guatemala

Authors: Escobar Jímenez, Nancy; Ranero Meneses, Jorge; Chocó-Cedillos, André
( 0 downloads)
Abstract

The most common coagulation disorder in the intensive care unit is thrombocytopenia. Considering the fundamental role of platelets in hemostasis and as markers of disseminated intravascular coagulation, a significant decrease in platelet count is alarming in the context of septic patients, and it is known to be a predictor of death. The objective was to compare the ability of the platelet count with the Sequential Organ Failure Assessment (SOFA) to predict death in patients with severe sepsis or septic shock. A longitudinal study was conducted with a sample of 29 consecutive cases evaluated during January to December 2015 in the Intensive Care Unit of the General Hospital of Diseases (HGE) of the Guatemalan Social Security Institute. Platelet and SOFA counts were performed at the first and the fifth day of hospitalization, documenting the outcome of the patients. Of the total, 51.7% of the patients were men and 48.3% were women, with an average age of 62.0 (16.9) years, median SOFA on admission of 10 units (Q1=4, Q3=14), and platelet median on admission of 196000 (Q1=100000, Q3=250000). The univariate association between thrombocytopenia and death was significant (p = .021, RR = 2.45, CI 95% [1.21, 4.99]). According to a Bootstrap test, there is no significant difference between the predictive capacity of SOFA and platelet count (p = .965). It was concluded that the presence of thrombocytopenia is a simple predictor of death in patients with severe sepsis or septic shock, with similar capacity to SOFA

Keywords: Organ dysfunction scores, platelet count, sepsis, septic shock
Determinants of perceived health after suffer from depression through the Spanish health survey 2017

Determinants of perceived health after suffer from depression through the Spanish health survey 2017

Authors: Siles-López, David; Fernández-Bianqui, Tatiana
( 0 downloads)
Abstract

The study about the effect of medicine on perceived health is wide and necessary. In mental health issues, perceived health could act as a determinant. In case of depression, a better perceived health could help in the medical treatment. In this article, some relevant variables from the Spanish health survey of 2017 have been analyzed, with the aim of contrasting the effect of some essential variables on the perceived health such as the use of homeopathy and antidepressants, nationality, age, or education level. This article shows positive and significant results for using both, homeopathy and antidepressants, in order to get a good or a very good perceived health. Both treatments are useful, but homeopathy has the advantage of having no side effects. Moreover, for the very bad perceived health status, the use of homeopathy does not get a worse perceived health

Keywords: health survey, depression, homeopathy, antidepressants
Phylogenetic analysis of HIV-1 variants of a comprehensive HIV clinic in Guatemala, through the subtyping of the pol-HIV-1 region sequences obtained during the period 2010-2015

Phylogenetic analysis of HIV-1 variants of a comprehensive HIV clinic in Guatemala, through the subtyping of the pol-HIV-1 region sequences obtained during the period 2010-2015

Authors: Oliva-Castillo, Ana; Lau-Bonilla, Dalia
( 0 downloads)
Abstract

The HIV genome contains nine genes, three of these genes (gag, pol, and env) encode structural proteins. There are two main variants of this virus, HIV-1 and HIV-2. The first one (HIV-1) is the cause of most infections worldwide, of which nine subtypes and 58 circulating recombinant forms (CRF) have been identified. In Central America, subtype B of HIV-1 is the cause of the majority of HIV positive cases. In Guatemala, it has been reported the presence of subtype B, recombinant forms BF1 and subtype C. However, no phylogenetic analysis has been performed to indicate the variants of this subtype. The aim of the study was to subtype 400 sequences of the pol region of HIV-1, of samples that were obtained from a care clinic during the period 2010 to 2015. To determine the different subtypes of HIV-1 present in Guatemala, the subtyping of the sequences obtained by the genotype test, in FASTA format, was performed with REGA HIV-1 Subtyping Tool - Version 3.0. In order to determine the relationship between HIV-1 variants, an alignment of sequences and phylogenetic trees was performed using the Neighbor Union and Maximum Likelihood method with 100 bootstrap replicas, with the MEGA 7.0.21 program. It was determined that the subtypes with the highest prevalence of the studied sequences are the subtype B (71.5 %), recombinant BD (16.75 %), and subtype B-like (7.75 %)

Keywords: HIV, HIV-1, subtyping, subtype B
Amylase production of strains of anamorphic fungi isolated from leaf litter of Quercus sp.

Amylase production of strains of anamorphic fungi isolated from leaf litter of Quercus sp.

Authors: Figueroa Ceballos, Ricardo; Morales Esquivel, Osberth; Bran González, María del Carmen
( 0 downloads)
Abstract

Anamorphic fungi are a group of microorganisms of great importance because they produce a wide variety of substances as part of their secondary metabolism, as well as various enzymes useful in the degradation of different substrates. One of these enzymes are amylases, which degrade the starch to dextrin, maltose or free glucose. Therefore, having industrial applications for the manufacture of detergents, food, and textiles. In this study we evaluated the potential of 40 strains of anamorphic fungi isolated from Quercus sp. leaf litter collected in the Municipal Regional Park “Astillero Municipal de Tecpán” in Chimaltenango (N 14º 46' 48.81", O 91º 0' 27.42"), and the Ecological Park “Senderos de Alux” in San Lucas Sacatepéquez (N 14º 36' 43.41", O 90º 38' 15.92"). The production of amylases was evaluated through the index of enzymatic activity, which was evidenced by the detection of a degradation halo on starch agar, as well as by the measurement of the amylolytic activity of enzymatic extracts. Of the strains evaluated, 37 (95%) produced amylases. The amylolytic activities of the anamorphic fungi native strains correspond with those reported for species of industrial use. The strain that showed the highest amylolytic activity (625 (13.09) UA/dl) was Virgaria nigra SL12517, which is similar to that reported for other fungi used in industrial processes. This shows the amylolytic potential of anamorphic fungi of Quercus sp. leaf litter

Keywords: enzymes, degradation, amylolytic capacity

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