Determination of Cellular Processing Rates for a Trastuzumab-Maytansinoid Antibody-Drug Conjugate (ADC) Highlights Key Parameters for ADC Design Journal title: The AAPS Journal Authors: Katie F. Maass, Chethana Kulkarni, Alison M. Betts, K. Dane Wittrup Subject(s): Medicine
A Mechanistic Pharmacokinetic Model Elucidating the Disposition of Trastuzumab Emtansine (T-DM1), an Antibody–Drug Conjugate (ADC) for Treatment of Metastatic Breast Cancer Journal title: The AAPS Journal Authors: Brendan Bender, Douglas D. Leipold, Keyang Xu, Ben-Quan Shen, Jay Tibbitts, Lena E. Friberg Subject(s): Medicine
