A Neutralizing Antibody Assay Based on a Reporter of Antibody-Dependent Cell-Mediated Cytotoxicity Journal title: The AAPS Journal Authors: Yuling Wu, Jia J. Li, Hyun Jun Kim, Xu Liu, Weiyi Liu, Ahmad Akhgar, Michael A. Bowen, Susan Spitz,... Subject(s): Medicine
Measurement of Free Versus Total Therapeutic Monoclonal Antibody in Pharmacokinetic Assessment is Modulated by Affinity, Incubation Time, and Bioanalytical Platform Journal title: The AAPS Journal Authors: Jeffrey J. Talbot, Dominador Calamba, Melody Pai, Mark Ma, Theingi M. Thway Subject(s): Medicine
Development of a Generic Anti-PEG Antibody Assay Using BioScale’s Acoustic Membrane MicroParticle Technology Journal title: The AAPS Journal Authors: Huijin Dong, Johanna R. Mora, Catherine Brockus, Shannon D. Chilewski, Robert Dodge, Colin Merrifiel... Subject(s): Medicine
Assay Formats: Recommendation for Best Practices and Harmonization from the Global Bioanalysis Consortium Harmonization Team Journal title: The AAPS Journal Authors: Sherri Dudal, Daniel Baltrukonis, Rebecca Crisino, M. Jaya Goyal, Alison Joyce, Karolina Öst... Subject(s): Medicine
Simultaneous Analysis of Multiple Monoclonal Antibody Biotherapeutics by LC-MS/MS Method in Rat Plasma Following Cassette-Dosing Journal title: The AAPS Journal Authors: Hongyan Li, Robert Ortiz, Linh T. B. Tran, Hossein Salimi-Moosavi, Jennifer Malella, Christopher A.... Subject(s): Medicine
Theoretical Considerations and Practical Approaches to Address the Effect of Anti-drug Antibody (ADA) on Quantification of Biotherapeutics in Circulation Journal title: The AAPS Journal Authors: Marian Kelley, Ago B. Ahene, Boris Gorovits, John Kamerud, Lindsay E. King, Thomas McIntosh, Jihong... Subject(s): Medicine
What is the Likelihood of an Active Compound to Be Promiscuous? Systematic Assessment of Compound Promiscuity on the Basis of PubChem Confirmatory Bioassay Data Journal title: The AAPS Journal Authors: Ye Hu, Jürgen Bajorath Subject(s): Medicine
Ligand-Binding Assays in the 21st Century Laboratory: Recommendations for an Automated Data Interchange Process Journal title: The AAPS Journal Authors: Sheldon S. Leung, Joel Usansky, Robert Lynde, Theingi Thway, Robert Hendricks, David Rusnak Subject(s): Medicine
Ligand Binding Assays in the 21st Century Laboratory: Platforms Journal title: The AAPS Journal Authors: Franklin P. Spriggs, Zhandong Don Zhong, Afshin Safavi, Darshana Jani, Narasaiah Dontha, Anita Kant,... Subject(s): Medicine
Ligand Binding Assays in the 21st Century Laboratory: Automation Journal title: The AAPS Journal Authors: Ago B. Ahene, Chris Morrow, David Rusnak, Susan Spitz, Joel Usansky, Holger Pils, Francesca Civoli,... Subject(s): Medicine
Ligand Binding Assays in the 21st Century Laboratory: Recommendations for Characterization and Supply of Critical Reagents Journal title: The AAPS Journal Authors: Denise M. O’Hara, Valerie Theobald, Adrienne Clements Egan, Joel Usansky, Murli Krishna, Jul... Subject(s): Medicine
Development and Advanced Validation of an Optimized Method for the Quantitation of Aβ42 in Human Cerebrospinal Fluid Journal title: The AAPS Journal Authors: Valerie C. Cullen, Ross A. Fredenburg, Cindy Evans, Phyllis R. Conliffe, Michael E. Solomon Subject(s): Medicine
Bioanalytical Approaches to Quantify “Total” and “Free” Therapeutic Antibodies and Their Targets: Technical Challenges and PK/PD Applications Over the Course of Drug Development Journal title: The AAPS Journal Authors: Jean W. Lee, Marian Kelley, Lindsay E. King, Jihong Yang, Hossein Salimi-Moosavi, Meina T. Tang, Jia... Subject(s): Medicine
Comparing Exponentially Weighted Moving Average and Run Rules in Process Control of Semiquantitative Immunogenicity Immunoassays Journal title: The AAPS Journal Authors: Troy E. Barger, Lei Zhou, Michael Hale, Michael Moxness, Steven J. Swanson, Narendra Chirmule Subject(s): Medicine
Assessment of a Spectrophotometric Assay for Monoacylglycerol Lipase Activity Journal title: The AAPS Journal Authors: Nadine M. Ulloa, Dale G. Deutsch Subject(s): Medicine
