A Case Control Study of Procalcitonin as A Novel Bio Marker in Sepsis
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2017, Vol 16, Issue 4
Abstract
Background: Sepsis is a leading cause of mortality in critically ill patients .Early diagnosis of sepsis followed by appropriate treatment decreases mortality and morbidity.The aim of this study is to assess the role of procalcitonin as a marker in the early diagnosis of sepsis. Methods: A total of 50 patients with sepsis admitted to AMCU of seven hills hospital ,Visakhapatnam from 1- 11-2015 to 1-11 -2016 were included in the study.Another 50 healthy persons with no clinical or biological data of infection ,age and sex matched were included as a control group.Subjects were subjected to a thorough history taking and routine laboratory investigations.Serum procalcitonin was measured using Elecys PCT assay on Roche Cobas e411 analyser.W.B.C was estimated by Sysmex xs -1000i Hematology Analyser. Results:Mean levels of PCT and WBC in cases were significantly higher than in control groups,p<0.001.when compared PCT showed a direct positive correlation with WBC. Conclusion:PCT alone or combined with WBC is a useful biomarker in early diagnosis of sepsis.
Authors and Affiliations
Dr. B. Preethi, Dr. M. Roopalatha, Dr. C. Ramakrishna, Dr. S. Sanjeevi Rao, B. Venkateswara Rao
Keywords
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- EP ID EP595538
- DOI 10.9790/0853-1604094549.
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