A Case of Acute Lymphoblastic Leukemia with Isolated Orbital Relapse
Journal Title: Meandros Medical and Dental Journal - Year 2018, Vol 19, Issue 2
Abstract
Acute lymphoblastic leukemia (ALL) is the most common malignancy of childhood. Central nervous system is the most frequent place of both at the onset and relapse of the disease, but orbital involvement is rarely seen. A seven-year-old girl diagnosed with high risk ALL and Turkish ALL-Berlin Frankfurt Münster (BFM)-2000 high risk group treatment was given. However, after induction and consolidation treatments, before the maintenance treatment she had blindness in her right eye. Ophthalmologic examination her visual acuity was fingers to count in two meters. In her right eye there was exudative retinal detachment and her orbital magnetic resonance imaging (MRI) showed that, there was a mass lesion in the posterior of right orbital globe, on the neighbourhood of optic disc, consistent with metastasis. After ALL-REZ-BFM-2002 relapse protocol treatments and radiotherapy her visual acuity was increased to 6/10. In control orbital MRI regression of mass lesion size was established. Bone marrow transplantation was planned. Orbital involvement is rarely seen in leukemia, but it is responsive to chemotherapy and radiotherapy combination.
Authors and Affiliations
Aziz Polat, Funda Özgürler Akpınar, Yasemin Işık Balcı, Semra Acer, Ali Koçyiğit, Havva Evrengül
Keywords
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- EP ID EP382194
- DOI 10.4274/meandros.2066
- Views 133
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