A case of pseudotumor cerebri associated with idiopathic hypopara-thyroidism and vitamin B12 deficiency
Journal Title: Ege Tıp Dergisi - Year 2015, Vol 54, Issue 3
Abstract
Idiopathic hypoparathyroidism is a heterogeneous disorder rarely involved in the etiology of pseudotumor cerebri, and characterized by low levels of parathormone accompanying hypocalcemia, hyperphosphatemia and vitamin D deficiency. A 38-year-old female patient was admitted to our clinic with the complaints of headache and blurred vision. Her neurological examination revealed bilateral papilledema which was more prominent in the left eye. Cranial magnetic resonance imaging findings of the patient were within normal ranges and cerebrospinal fluid (CSF) pressure was 270 mmH2O which was measured through a lumbar puncture (LP), then the patient was diagnosed with pseudotumor cerebri. Laboratory assessment revealed low parathormone (PTH) and vitamin D levels accompanying hypocalcemia and hyperphosphatemia; and the patient was diagnosed with idiopathic hypoparathyroidism. In her followup, no decline was observed in CSF pressure and in the repeated laboratory assessments, a decrease in the vitamin B12 level was observed, thus vitamin B12 supplementation was added to her treatment. In control LPs, CSF pressure (190 mmH2O) decreased as the blood calcium (Ca) and vitamin B12 levels increased.
Authors and Affiliations
Pınar AKGÜL, Müge ÖZSAN, Remzi YİĞİTER, Mustafa YILMAZ, Aylin AKÇALI, Münife NEYAL, Mehmet Ali ELÇİ, Sırma GEYİK
A five-year retrospective evaluation of t(4;11) MLL/AF4 translocation results with real time RT-PCR in acute lymphoblastic leukemia patients
Aim: t(4,11) is a chromosomal abnormality formed by the translocation MLL-AF4, which is the result of the fusion of the AF4 gene, localized on 4q21 chromosomal band, to the MLL gene, localized on 11q23 chromosomal band....
Prospective-observational evaluation of the 50 meningomyelocele neonates
Aim: We aimed to analyze the clinical outcomes and maternal sociodemographic features of the patients followed in the neonatal intensive care unit with meningomyelocele diagnosis. Materials and Methods: Babies with meni...
Osteoporozda farmakolojik tedavi
Osteoporoz tedavisinde kullanılan ajanlar genellikle iyi tolere edilir ve oldukça etkindirler. Bisfosfonatlar ve RANKL inhibitörü denosumab gibi antirezorptifler en sık kullanılan osteoporoz ilaçlarıdır. Bu ajanlar postm...
Anti-TNF therapy-induced autoimmunity
Aim: Anti-TNF therapy has recently emerged as an effective therapy for treating rheumatic diseases. With this increasing use and longer follow-up periods of treatment, various adverse effects are emerging. These adverse...
Serebral palsili hastaların demografik ve klinik özellikleri
Amaç: Çalışmamızın amacı serebral palsi (SP) polikliniğinde SP tanısı ile takip ve tedavisi yapılan hastalarımızın demografik ve klinik özelliklerini belirlemektir. Gereç ve Yöntem: Düzenli takibi olan 577 hastanın bilgi...