A Case Report of Edward Syndrome and Review of 152 Similar Cases Published in Various Journals
Journal Title: Scholars Journal of Applied Medical Sciences - Year 2014, Vol 2, Issue 2
Abstract
First described by Edward in 1960, this is the second most common autosomal trisomy after Down’s syndrome. Incidence of Edward syndrome varies from 1 in 3500 to 1 in 7000. All the cases has been collected from internet published in various journals and are available as full article free to access and refer. One case is from our institution. Total 152 cases of Edward syndrome has been reviewed which are proved by cytogenetic study. The male to female ratio is 1.3:1. In more than 50% of cases, both maternal and paternal age is less than 30 years. Most common abnormality associated with cardiovascular system followed by extremities, urinary system, head and neck, gastrointestinal tract and genitals. In conclusion, Edward syndrome is a rare genetic disorder associated with multisystem involvement. Hence, data collection and frequent review of cytogenetically proven cases is must to study in detail about the association of genetic defect and organ system involved. It is also helpful to compare with other known genetic disorder.
Authors and Affiliations
Satish Arakeri, Uroos Fatima, Ramkumar KR, Noori Khalid
Keywords
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