A CLINICAL STUDY ON THYROID DYSFUNCTIONS IN PREGNANCY AND ITS EFFECT ON MATERNAL AND NEONATAL OUTCOME
Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2018, Vol 7, Issue 12
Abstract
BACKGROUND Thyroid dysfunction in pregnancy is a common occurrence. Thyroid dysfunction in pregnancy has adverse effects on maternal and neonatal outcome. So, pregnancy is seen as a risk factor in the occurrence of thyroid dysfunctions. The purpose of this study was to estimate the prevalence of different thyroid dysfunctions in pregnancy and to study their effects on foetomaternal outcome. MATERIALS AND METHODS This was a prospective, observational study conducted in the Department of Obstetrics and Gynaecology, GSVM Medical College, Kanpur, UP, India, over a period of 2 years (Oct. 2015 - Oct. 2017) in 1268 pregnant women attending the OPD and IPD of our hospital. The first line screening test used for diagnosis of thyroid dysfunction was serum TSH level by CLIA method. RESULTS The study was conducted in 1268 pregnant women. They were screened for thyroid dysfunctions by measuring serum TSH level. Thyroid dysfunction was found in 196 pregnant women (prevalence 15.5%), out of which 11.2% patients have subclinical hypothyroidism, 3.5% patients have overt hypothyroidism and 0.8% patients have hyperthyroidism. Maternal complications included preeclampsia (15.8%), abortions (12.2%), abruptio placentae (7.14%), PPH (4.6%), PPROM (7.14%) and anaemia (22.4%). Neonatal complications included preterm birth (11.2%), low birth weight (10.2%), IUGR (7.14%), still birth and IUD (6.6%), NICU admissions (13.7%) and low APGAR score (13.2%). CONCLUSION Thyroid dysfunctions in pregnancy are increasing and adversely affect maternal and neonatal outcome, therefore all antenatal women should be screened for thyroid dysfunctions so as to minimise the adverse outcomes.
Authors and Affiliations
Renu Gupta, Shaily Agarwal, Kiran Pandey, Neena Gupta, Uruj Jahan, Yashwant Kumar Rao, Pundrik Kumar Gupta
Keywords
Related Articles
- EP ID EP412073
- DOI 10.14260/jemds/2018/344
- Views 166
- Downloads 0
ROLE OF HIGH RESOLUTION COMPUTED TOMOGRAPHY CHEST (HRCT) IN SUSPECTED CASES OF PAEDIATRIC TUBERCULOSIS WHERE CHEST X-RAY IS NORMAL
BACKGROUND Childhood TB contributes to a large proportion (15 - 20%) of all TB patients in developing countries. As per National guidelines on diagnosis and treatment of Paediatric Tuberculosis in India, all efforts shou...
RETROSPECTIVE ANALYSIS OF MALIGNANT EYELID TUMOURS IN A TERTIARY CARE CENTRE– 10 YEARS SURVEY
BACKGROUND Eyelid tumours are by far the most common neoplasms encountered in ophthalmic clinical practice and are estimated to represent more than 90% of all ophthalmic tumours. The aim of the study is to evaluate and c...
SCROTAL ABDOMEN: A CASE REPORT
Scrotal abdomen or Giant Inguino scrotal hernia, though an uncommon entity presents with operative dilemma as there are no standard surgical procedure. We present a case of giant inguinoscrotal hernia of a 49...
DENTAL IMPLANT MATERIALS, IMPLANT DESIGN, AND ROLE OF FEA- A BRIEF REVIEW
BACKGROUND A dental implant is utilised to hold the counterfeit tooth into its legitimate position in the human jaw. It fills the need of characteristic root which is there in a normal tooth. Implant design, implant stab...
GROSS ANATOMICAL FEATURES OF LEFT ATRIAL APPENDAGE
Left auricle has unique developmental, anatomical and physiological properties. The Left Atrial Appendage (LAA) lies within the fixed, relatively immobile confines of pericardium. Although in the past it has b...