A CLINICAL STUDY TO IDENTIFY THE PREVALENCE OF ASYMPTOMATIC BACTERIURIA IN TYPE II DIABETIC PATIENTS AT RAJIV GANDHI INSTITUTE OF MEDICAL SCIENCES, SRIKAKULAM
Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2018, Vol 7, Issue 3
Abstract
BACKGROUND Diabetes mellitus is one of the common diseases affecting a large number of population throughout the world. (1) Urinary tract infection is the most common infection in diabetic patients. Many UTIs are asymptomatic and whether symptomatic UTI are preceded by asymptomatic bacteriuria (ASB) is not known. Asymptomatic bacteriuria can lead to symptomatic urinary infection as well as increase in tendency for chronic kidney disease (CKD) and renal failure as one of the long-term adverse effects. The prevalence rate of ASB in diabetic women are 9% - 29% among females and 0.7% - 11% in males. (2,3) The most common aetiological agents(4,5,6) in asymptomatic bacteriuria are Klebsiella pneumonia, E. coli, Enterobacter spp., Streptococcus agalactiae, Enterococcus faecalis, Coagulase Negative Staphylococci (CONS) and Streptococcus pyogenes. UTI is a common problem among females and non-diabetics also, hence a study was conducted to know the asymptomatic bacteriuria among type 2 diabetics and non-diabetics. MATERIALS AND METHODS Outpatients attending medicine OPD in Rajiv Gandhi Institute of Medical Sciences, Srikakulam, were taken into the study. A crosssectional study was done to know the prevalence of asymptomatic bacteriuria in Type II Diabetic patients among the diabetics (Group A) and non-diabetics (Group B); 103 patients in study population (Group A) and 50 patients in control group (Group B) were taken; 50% of the sample size were taken for control group. RESULTS Out of 153 randomly selected patients 103 were found to be diabetic; hence, they were recruited in the study group. Out of 103 patients, 58 (56.3%) were females and 45 (77%) were males in the study population. All the patients were in the age group of 30- 80 years with an age of 42 + 10.6 years (Table 1) (Graph 1). Non-diabetic 50 patients were included in the control group, who were in the age group of 75 years with the mean age of 48 + 8.9 years. Control group consisted of 28 (56%) males and 22 (44%) females. CONCLUSION The incidence and prevalence of ASB is high in diabetic population compared to non-diabetic group. (5) ASB is one of the important risk factors for renal complications in Diabetic population. Diverse pathogenic microbial diaspora are responsible for ASB. Close monitoring of antibiotic sensitivity shall improve the control of ASB and thereby score over the risk reduction of renal complications in diabetic patients. To prevent lifetime complications, it is recommended periodic/ regular screening for UTI as it has a symptomatic presentation.
Authors and Affiliations
Bongu Srinivasa Rao, Gopal Rao A, Sharath Babu Naik Z
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