A Clinicopathological Study of Carcinoma Breast Specimens: Four Year Retrospective Study
Journal Title: Indian Journal of Pathology: Research and Practice - Year 2017, Vol 6, Issue 3
Abstract
Introduction: Cancer is one of the major health issues worldwide including India. Breast cancer is by far the most frequent cancer in females with rising incidence and usually presents at advanced stage at diagnosis making the outcome poor, however aggressive the treatment may be and leading to disproportionately higher mortality rates. Aims and Objectives: To study the age, incidence, clinical presentation and histomorphological pattern of carcinoma breast in all mastectomy specimens. Methodology: Four year retrospective study of 170 mastectomy specimens received in the department of pathology from Jan 2012 to Dec 2016. All the sections were retrieved and diagnosis were confirmed and the necessary clinical data was obtained from records department. Histological grading were done according to Modified Scraff-Bloom-Richardson Method. Results: The commonest presenting symptom was painless lump (65% of patients) with slight left breast predominant involvement (55%). The most common site of location were in upper outer quadrant (35%) and the least in subareolar region (3%). Among the histological varieties invasive duct carcinoma not otherwise specified was the commonest (83%) and the least was tubular carcinoma (0.5%). Majority of the patients were between 41-50 years (45%). 56% of cases showed evidence of metastasis in lymph nodes. In our study, 52.1% of carcinomas were in Grade I, 41.3% were in Grade II, and 6.6% were Grade III. Conclusion: Carcinoma breast is affecting young to middle age group and the number of cases increasing every year and we cannot prevent this cancer, all we can do is Breast Awareness and screening programmes is the need of the hour. Keywords: Breast; Mastectomy; Infiltrating Duct Carcinoma; Tumor Size; Grade.
Authors and Affiliations
Anusha N.
Seroprevalence of Transfusion Transmissible Infections (TTIs) in Blood Donors: A 5 Year Study
Objective: Blood transfusion is an important mode of transmission of infections to recipients. With every one unit of blood transfusion there is 1% chance of transfusion related complications including Transfusion Transm...
Premalignant Lesions and Incidental Carcinoma in Clinically Diagnosed Benign Prostatic Hyperplasia (BPH)
Background: Histological examination of the prostate must also include the description of some important aspects which are present associated with Benign Prostatic Hyperplasia (BPH) and which may condition the progressio...
Rainbows of Ovarian Lesions in Department of Pathology in a Tertiary Care Hospital
Background: Histopathological examination remains the gold standard for diagnosis of ovarian tumours. Morphological diversity of ovarian tumours poses many challenges in diagnosis. It is important to have knowledge regar...
Recommendation for Modification in the Bethesda System for Reporting of Thyroid Cytopathology: A Study in a Tertiary Care Hospital
Introduction: Thyroid is the endocrine organ situated in the midline of the neck.Its pathology varies from nutritional disorders like multinodular goiter to high grade malignancy like anaplastic carcinoma. Since the thyr...
Fungal Disease Complex on a Nutritional, Medicinal and Economically Important Forage Crop - Maize from Bahraich (U.P.) India
During survey for the foliicolous fungi from diversified habitats of Bahraich (U.P.) India the authors came across an important crop for the locality Zea mays Linn. which belongs to PoaceaeĀ the grass family is commonly...