A Comparative Analysis of Quality of Life in Cervical Cancer Patients Undergoing Conventional Vs Conformal Radiotherapy
Journal Title: International Journal of Contemporary Medical Research - Year 2017, Vol 4, Issue 1
Abstract
Introduction: Gynaecological cancers are most common group of malignancies in women, accounting for approximately 18% of all cancers of women worldwide. However, these patients after being cured face a variety of treatment and disease related side effects frequently that affect their quality of life (QOL) during, immediately and after treatment. The aim of the present study is to compare the quality of life in cervical cancer patients after undergoing conventional vs conformal radiotherapy. Material and methods: The present study was conducted in Department of Radiation Oncology; Basavatarakam Indo American Cancer Hospital and Research Institute, Banjara Hills, Hyderabad. The study was conducted from August 2015 to June 2016. The study consisted of 60 cervical cancer patients who had completed a minimum of 2 years of follow up after the completion of treatment with chemo-radiation. The Cross sectional study divided the patients of cervical cancer in two arms. In Group A/ ARM 1, patients treated by Intensity modulated Radiotherapy (IMRT) was included. In Group B/ARM 2, patients treated by conventional RT (CXRT / Conventional) were included. Quality of life of patients was assessed using EORTC QLQ-C30 and QLQ-CX24 modules. Patient’s details regarding demographic history, examination findings, stage of disease and treatment received were collected from hospital records. Mean and standard deviation were used to describe results of level of quality in sample by using Windostat Version 9.2. Comparison of two arms was done using t test. Results: The present study included 60 patients of cervical cancer. The most common age group at diagnosis was 45 to 55 years and the mean age at the time of diagnosis was 48 years. Squamous cell carcinoma was the most commonly seen cancer histologically. There were two cases of Stage IB in group A and 1 case each of stage IIA in Group A and Group B. No statistically significant differences between both arms were observed in global health, functioning, fatigue, constipation, diarrhoea, financial difficulties and there is no difference in EORTC QLQ-C30 QOL scores in both arms of the study. Conclusion: All health care providers should address regarding sexual life and provide guidance and assurance after treatment. In our study no significant difference was found in the quality of life amongst patients undergoing conventional or conformal radiotherapy
Authors and Affiliations
Chatharaju Swarna Kumari, Abdul Wahab Abdullah, Alluri Krishnamraju
Keywords
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