A comparative community based cross-sectional study of lipid profile among healthy urban and rural local ethnic Mising population in a district of upper Assam
Journal Title: Medpulse International Journal of Biochemistry - Year 2018, Vol 7, Issue 2
Abstract
Background: Abnormalities in lipid profile are important risk factors for cardiovascular disease. Ethnicity, cultural and socioeconomic characteristics influence the lipid profile in different populations. Mising ethnic population of Assam traditionally consume boiled pork, dried fish and rice beer with low use of cooking oil. Many of them have migrated from rural to urban areas of Assam with corresponding changes in thei r diet and lifestyle. Aims and objectives: To assess and compare the lipid profile of healthy rural and urban Mising population of Dibrugarh district, Assam, India. Materials and Methods: After Institutional ethics committee (IEC) clearance and written informed consent, we estimated lipid profile of 100 healthy subjects between 18-65 years from both genders of urban and rural Mising population in Dibrugarh district of upper Assam from 1stOctober 2009 to 30thSeptember 2010. Subjects with hereditary familial hypercholesterolemia, chronic diseases like diabetes mellitus or pre-existing cardiovascular disease, pregnant women, subject with medication for any other diseases or usage of oral contraceptives were excluded. After interview and clinical examination of the subjects, fasting blood samples were collected for estimation of total cholesterol, triglycerides and HDL, LDL, VLDL cholesterol (mg/dl). Data were recorded in a proforma and serum lipid values were expressed as Mean ± SD. Statistical analysis for significance of differences in means and age and gender variations was performed in GraphPadQuickCalcs statistical software, using unpaired Student’s t test, where P < 0.05 was considered statistically significant at 95% Confidence interval. Observations and Results: We observed statistically significant higher levels of mean serum total cholesterol and LDL and significantly lower HDL cholesterol in urban compared to rural Mising population, but no significant difference was found in the triglyceride and VLDL values. Conclusion: Urban population has adverse lipid profile compared to the rural population among Mising ethnic group of Assam.
Authors and Affiliations
Kailash Gairola, Javin Bishnu Gogoi, RohiniKanta Goswami, Kingshuk Lahon
Keywords
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