A comparative study between the efficacy of fentanyl with bupivacaine 0.5%, buprenorphine with bupivacaine 0.5% and midazolam with bupivacaine 0.5% in spinal anesthesia for lower abdominal surgeries
Journal Title: Medpulse International Journal of Anesthesiology - Year 2017, Vol 8, Issue 1
Abstract
Background and Objectives: The major feared consequences of surgery experienced by the patient is pain, both physically and psychically, thus Providing the effective analgesia in post surgical period to the patients becomes challenging in the speciality of anesthesia. Multidimensional analgesic approaches like parenteral analgesics or regional analgesia with spinal adjuvants like opioids, benzodiazepines and a2 agonists are commonly practiced. The main intention of this study is to compare the analgesic efficacy of Fentanyl (A), Buprenorphine (B), midazolam (C) with bupivacaine intrathecally in lower abdominal surgeries. Materials and Methods: A Seventy five American society of anaesthesiologist physical status I and II patients scheduled for various surgeries in lower abdomen were identified and randomised into three groups of twenty five patients each and studied. Group A, B and C received fentanyl, buprenorphine and midazolam with hyperbaric bupivacaine respectively. Patients involved in studies were studied for intraoperative hemodynamic changes, onset of sensory, motor blockade, total period of analgesia, and peri operative complications for twenty four hrs post surgery. Visual Analog Score (VAS) was recorded at the end of surgery and hourly up to 8 hours and the time for rescue dose of analgesia was noted. ANOVA, SPSS version 16 was used for analysis. Results: We have found that all the three drugs provided pain relief for various lower abdominal surgeries with hemodynamic stability. Duration of analgesia was significantly higher in buprenorphine than fentanyl and midazolam groups (44616.99 mins Vs 22519.37 mins and263 14.63 mins with ‘P’ value < 0.01). Conclusion: supplementing bupivacaine with buprenorphine 60 micrograms intrathecally provides effective significant pain relief for longer period of time than fentanyl and midazolam in peri operative period.
Authors and Affiliations
M Dhakshinamoorthy, V Anandaraj
Keywords
Related Articles
- EP ID EP440490
- DOI 10.26611/1015812
- Views 144
- Downloads 0
Evaluation of efficacy of intravenous magnesium sulphate in general anaesthesia cases for post operative analgesia
Background: Surgical procedures are associated with tissue injury and postoperative pain after surgical interventions. Aim: To evaluate the efficacy of intravenous magnesium sulphate on post operative analgesia following...
Ultrasound guided tap block: Comparison of analgesic efficacy of levobupivacaine and ropivacaine
Study objective: Ultrasound guided transverse abdominis plane (TAP) block is an effective method of providing postoperative analgesia in patients undergoing abdominal surgeries. We compared the postoperative analgesic ef...
A Study effectiveness of hemodynamic responses to laryngoscopy and endotracheal intubation to intravenous dexmedetomidine with respect to different doses
Background: The process of intubation is a noxious stimuli leading to a period of extreme haemodynamic stress and is accompanied with intense sympathetic activity marked by tachycardia and hypertension. Aims and Objectiv...
Role of Inj. Dexamethasone for prevention of post operative nausea and vomiting in laparoscopic surgeries
Aims and Objectives: To study the role of inj. Dexamethasone for early and late Post Operative Nausea and Vomiting in laparoscopic surgeries. And also to record side effects of dexamethasone. Study Design: Prospective, r...
The efficacy of two different doses of gabapentin (300mg and 600mg) along with NSAID (diclofenac transdermal patch 100mg) in postoperative pain management following abdominal hysterectomy
Context: Gabapentin, an antiepileptic drug has a role in acute postoperative pain management due to its anti hyperalgesic property. Pre-emptive analgesia is the recent concept in multi modal pain management. The purpose...