A Comparative Study of Anaesthetic & Haemodynamic Effects of Intrathecal Dexmedetomidine & Clonidine as Adjuvants To 0.5% Hyperbaric Bupivacaine.
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2019, Vol 18, Issue 1
Abstract
Introduction:Alpha 2 adrenergic agonists such as Dexmedetomidine & Clonidine are used as adjuvants for achieving multiple benefits in Spinal anaesthesia.Dexmedetomidine which is a new alpha 2 agonist has alpha 2: alpha 1 selectivity of eight times higher selectivity more than clonidine.Hence the present study was undertaken to compare Dexmedetomidine & Clonidine for use with intrathecal hyberbaric Bupivacaine. Results:In the present study it was noted that Dexmedetomidine 5µg when added to 12.5mg 0.5% hyberbaric bupivacaine had a faster onset of motor blockade and a longer duration of sensory blockade,motor blockade and a longer duration of analgesia when compared to Clonidine 30µg when added to 12.5mg 0.5% hyperbaric Bupivacaine. Conclusion:Thus from the present study it is proved that Dexmedetomidine a new alpha 2 agonist significantly prolongs the duration of 0.5% hyberbaric Bupivacaine when compared with Clonidine.
Authors and Affiliations
Dr. B. Trinath Kumar
Keywords
Related Articles
- EP ID EP432694
- DOI 10.9790/0853-1801064353.
- Views 54
- Downloads 0
4-Pin Technique of Management of Distal Both Bone Fracture of Forearm in Elderly
Introduction: Distal both bone fractures are one of the most common injury of an elderly who falls with flexed elbow, landing on the wrist. There is a wide variety of treatment options such as closed reduction and POP ca...
Sporadic Outbreaks of Diphtheria: A Three Year Study from a Tertiary Care Centre of Northeast India.
Diphtheria is an acute toxin mediated contagious febrile illness, predominantly in children, caused by the locally invasive Gram positive bacillus Corynebacterium diphtheriae. In developing countries, with increasing cov...
Subclinical Hypothyroidism in type 2 diabetes mellitus patients
Introduction: Diabetes mellitus (DM) is the most common metabolic disease and its prevalence is increasing rapidly. Studies have reported that there is thyroid dysfunction in Type 2 Diabetes Mellitus patients. Subclinica...
Preterm Labour, Pprom, Prom And Neonatal Outcomes Associated With Vaginal Infection: A Prospective Study
Purpose 1. To find the incidence of preterm labor, preterm premature rupture of membranes (PPROM) and premature rupture of membranes (PROM) in relation with vaginal infection. 2. Use of high vaginal swab to detect the or...
Evaluation of Supracostal Punctures in PCNL
Aim: Aim Of Our Study On Effective Stone Clearance Rate, To Analyze And Study The Intra And PostOperative Complications And To Study The Morbidity In Terms Of Hospital Stay.Materials And Methods: It Is A Prospective Stud...