A Comparative Study of Anaesthetic & Haemodynamic Effects of Intrathecal Dexmedetomidine & Clonidine as Adjuvants To 0.5% Hyperbaric Bupivacaine.
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2019, Vol 18, Issue 1
Abstract
Introduction:Alpha 2 adrenergic agonists such as Dexmedetomidine & Clonidine are used as adjuvants for achieving multiple benefits in Spinal anaesthesia.Dexmedetomidine which is a new alpha 2 agonist has alpha 2: alpha 1 selectivity of eight times higher selectivity more than clonidine.Hence the present study was undertaken to compare Dexmedetomidine & Clonidine for use with intrathecal hyberbaric Bupivacaine. Results:In the present study it was noted that Dexmedetomidine 5µg when added to 12.5mg 0.5% hyberbaric bupivacaine had a faster onset of motor blockade and a longer duration of sensory blockade,motor blockade and a longer duration of analgesia when compared to Clonidine 30µg when added to 12.5mg 0.5% hyperbaric Bupivacaine. Conclusion:Thus from the present study it is proved that Dexmedetomidine a new alpha 2 agonist significantly prolongs the duration of 0.5% hyberbaric Bupivacaine when compared with Clonidine.
Authors and Affiliations
Dr. B. Trinath Kumar
Keywords
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- EP ID EP432694
- DOI 10.9790/0853-1801064353.
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