Preterm Labour, Pprom, Prom And Neonatal Outcomes Associated With Vaginal Infection: A Prospective Study

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Preterm Labour, Pprom, Prom And Neonatal Outcomes Associated With Vaginal Infection: A Prospective Study

Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2017, Vol 16, Issue 12

Abstract

Purpose 1. To find the incidence of preterm labor, preterm premature rupture of membranes (PPROM) and premature rupture of membranes (PROM) in relation with vaginal infection. 2. Use of high vaginal swab to detect the organism in relation with vaginal infection. 3. Role of an appropriate antibiotic therapy for vaginal infection. Materials and Methods: A total of 90 patientswith gestational age above 28 weeks till term were included in the study.Women who presented with signs of PROM, PPROM and preterm labor were enrolled in study.The diagnosis of spontaneous rupture of the membranes was confirmed by inspection of the cervix for flow of amniotic fluid from the cervical canal, if leakage is not present than patient is asked to cough and leak is noticed. The amount, colour and smell of the fluid were assessed. Based on the findings of cervical dilatation and uterine contractions patients were categorized as preterm labor (uterine contractions 4/20ʺ/10ʹ, cervical dilatation ≥3cm in multi and >1.5cm in primi, effacement 30%) or threatened preterm labor (uterine contractions 3-4/< 20 /10, absent of cervical dilatation). Swab from the posterior fornix of the vagina were taken and sent for Gram’s staining and Culture and sensitivity.All the patients were monitored for sign of chorioamnionitis. Results: Preterm delivery (Birth prior to 37 WOG) occurs in 7-11 %, Delivery occurs prior to 34 WOG, neonatal mortality found in 75% (1/3rd) and 50% (1/2) developed neurological impairment as a long term sequel. Approximately 25-30% of preterm delivery found to be due to PPROM, among them 25-40% were associated with intrauterine infection. Conclusions: This study help us to find the microbiological correlation of preterm labour, PROM, PPROM in western part of Nepal, So that we can plan our treatment and prevent from neonatal mortality and other complications like neurological deficit

Authors and Affiliations

Mahaseth BK, Srivastav M, Das CR

Keywords

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EP ID EP250803
DOI 10.9790/0853-1612067983
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