Sporadic Outbreaks of Diphtheria: A Three Year Study from a Tertiary Care Centre of Northeast India.
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2018, Vol 17, Issue 7
Abstract
Diphtheria is an acute toxin mediated contagious febrile illness, predominantly in children, caused by the locally invasive Gram positive bacillus Corynebacterium diphtheriae. In developing countries, with increasing coverage of immunization, the incidence of the disease has declined. This study was carried out to know the incidence of diphtheria among 99 patients from suspected sporadic diphtheria outbreaks, admitted in a tertiary care centre of Assam in Northeast India, over a period of three years from January, 2013 to December, 2015. Throat swabs were collected and subjected to direct smear microscopy by Gram’s and Albert stains, and culture on Blood agar, Loeffler’s seum and Tellurite Blood agar media. C. diphtheriae was isolated in 26 cases. The highest culture positivity of 40% each was in age groups 5-9 and 10-14 years. Culture positivity was highest (62.5%) in non-immunized patients, and surprisingly, it was 31.57% in fully immunized patients. The study signifies re-emergence of diphtheria in this State calling for intensive monitoring and review of Universal Immunization Programme, and quality, storage and transport conditions of vaccines in the State.
Authors and Affiliations
Dr. Daiji Gogoi Mohan, Dr. Mayuri Gogoi, Dr. N. K Hazarika, Dr. Ajanta Sharma
Keywords
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- EP ID EP377487
- DOI 10.9790/0853-1707104245.
- Views 62
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