A comparative study of cytology versus histology in the salivary gland tumors
Journal Title: MedPulse -International Medical Journal - Year 2015, Vol 2, Issue 11
Abstract
Introduction: Salivary gland tumors are uncommon, amounting to approximately 3-10% of neoplasms of the head and neck region. However, a wide variety of tumors in these glands and insufficient tumor cells in aspiration cytology make the diagnosis difficult in some patients. The general rule in salivary gland neoplasms is: ‘smaller the gland, higher the rate of malignancy’. Thus, the rate of malignancy increases from 20%–25% in the parotid gland to 40%–50% in the submandibular gland and to 50%–81% in the sublingual glands and minor salivary glands. Aims and Objective: To assess the sensitivity and specificity of the Cytology in the diagnosis of the salivary gland tumors. Methodology: This was a prospective study conducted in the Departments of Pathology with aid from the surgical Department at tertiary care hospital from 2 years duration Jan 2012-Jan 2014. A total of 60 patients with salivary gland lesions who had undergone preoperative FNAC and had been diagnosed by subsequent histopathological examination were included in this study. Result: The sensitivity of the FNAC (Cytological test) was 80% and Specificity was 97.78%, Positive predictive value = 92.30%, Negative Predictive value =93.61%.Cytologically; In benign the majority of the lesions were Pleomorphic adenoma (28.33%), Warthinstumour (20.00%), Chronic sialadenitis (8.33%), Benign cystic lesion(8.33%), Lymphoepithelial cyst( 6.66%), Oncocytoma (5.00%), Basal cell adenoma(5.00%), Lymphangioma (3.33%).In malignant lesions majority of the lesions were Adenocarcinoma (6.67%) Mucoepidermoid carcinoma (5%) Acinic cell carcinoma (1.67%) Adenoid cystic carcinoma (1.67%). Histologically in Benign majority of the lesions were; Pleomorphic adenoma(25%) Warthinstumour (16.67%) Chronic sialadenitis (11.67%) Basal cell adenoma (8.33%) Lymphoepithelial cyst Lipoma (6.67%) Salivary duct cyst (3.33%). In majority of the malignant lesions diagnosed by histopathologically were Mucoepidermoid carcinoma (6.66%), Acinic cell carcinoma, (5.00%), Salivary duct SCC, (3.33%) Infiltrating salivary duct carcinoma,(3.33%), Myoepithelial carcinoma,(3.33%). Conclusion: The safe and sensitive and accurate method FNAC is useful to diagnose the Salivarygl and lesions pre-operatively.
Authors and Affiliations
Bharat Subhash Borole, Govinda Bhagwat Toke
Keywords
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