A Comparative Study of Dexmedetomidine and Clonidine in Post Spinal Anaesthesia Shivering
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2018, Vol 17, Issue 3
Abstract
Background: Shivering is known to be a frequent complication in patients undergoing surgery under regional anaesthesia. Dexmedetomidine and clonidine (α2 adrenergic agonist) have been used as a sedative agent and are known to reduce the shivering threshold. The aim of this study was to evaluate and compare the efficacy, haemodynamics and adverse effects of dexmedetomidine with those of clonidine, when used for control of post spinal anaesthesia shivering. Methods: A prospective , randomized and double blind study was conducted in 90 American Society of Anaesthesiologist Grade I and II patients of female sex, aged 18-45 years, scheduled for lower abdominal surgeries under spinal anaesthesia. The patients were randomised into three groups of 30 patients each. Group D received dexmeditomidine 0.5µg/kg , group C received clonidine 0.5µg/kg and group S (Control) received 5ml normal saline as intravenous bolus. Grade of shivering, onset of shivering, time of cessation of shivering, response rate and adverse effects were observed at scheduled intervals. Results: Time taken for cessation of shivering was less with dexmeditomidine when compared to clonidine.. Sedation profile was more with dexmeditomidine when compared to clonidine. However, there was not much difference in the adverse effects like nausea, vomiting, hypotention and bradycardia. Conclusion: Although both both dexmeditomidine and clonidine were effective in treatment of post spinal anaesthesia shivering, dexmeditomidine is more effective than clonidine with more sedation which provide comfort to the patients.
Authors and Affiliations
Rupendra Singh Thokchom, Maharabam Binarani, Heikham Kennedy Singh, Sanasam Sarat Singh, Takhelmayum Hemjit Singh, Sinam Praneshwari
Keywords
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- EP ID EP369368
- DOI 10.9790/0853-1703081520.
- Views 46
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