A Comparative Study of Dexmedetomidine As Adjuvants To Intrathecal Heavy Bupivacaine (0.5%) For Lower Abdominal Surgeries.
Journal Title: International Journal of Medical Science And Advanced Clinical Research (IJMACR) - Year 2019, Vol 2, Issue 1
Abstract
Introduction: Several adjuncts like adrenaline,opioids and alpha-2 adrenergic agonists are being used with local anaesthetics intrathecally for prolongation of intra-operative and post-operative analgesia and to reduce the side-effects of high doses of local anaesthetics.Aim: The present study was done to evaluate the onset and duration of sensory and motor block, hemodynamic effects, post-o perative analgesia and adverse effects of Dexmedetomidine or Fentanyl given intrathecally with hyperbaric 0.5% Bupivacaine. Materials And Methods: Sixty inpatients of ASA class I and II scheduled for various lower abdominal surgeries under Sub-Arachnoid Block were randomly divided into two groups of 30 each namely C (Control), D(Dexmedetomidine) and . All received 12.5mg hyperbaric bupivacaine plus 0.5 ml Normal Saline in Group C(Control),5 μ g Dexmedetomidine (diluted in preservative free Normal saline of 0.5ml) in Group D(Dexmedetomidine) and . The onset time to reach peak sensory and motor level, the regression time for sensory and motor block, hemodynamic changes and side-effects were noted. Results: The duration of sensory and motor block,rescue analgesia was significantly prolonged in Dexmedetomidine group when compared to that of Control group . CONCLUSION: Dexmedetomidine 5 μg seems to be a better neuraxial adjuvant to hyperbaric Bupivacaine.
Authors and Affiliations
Dr. Shahzad Akhter
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