A Comparative Study of Intrathecal Chloroprocaine and Ropivacaine in Day Care Perineal Surgeries
Journal Title: International Journal of Medical Science and Innovative Research (IJMSIR) - Year 2019, Vol 4, Issue 1
Abstract
Background: Chloroprocaine has recently been re-introduced into the market after being initially withdrawn due to concerns of neurotoxicity, and is being increasingly used of day care proedures. Ropivacaine is proven to have shorter PACU discharge times as compared to Bupivacaine. This study was designed to compare Chloroprocaine and Ropivacaine for spinal anesthesia in perineal day care procedures. Methods: A total of 90 patients were enrolled in this randomized double-blind study. Spinal anesthesia was achieved with 4ml of 0.5% Ropivacaine (n = 45) or 4ml of 1% Chloroprocaine (n = 45). The primary endpoint for the study was the time until reaching eligibility for discharge. Secondary outcomes included total requirements of rescue analgesic and patient satisfaction. Results: Average discharge time was significantly lower with Chloroprocaine (278±12.03 mins) as compared to Ropivacaine (304±10.64 mins). Duration of analgesia was significantly higher with Ropivacaine (170±12.61 mins). Total analgesic requirements were significantly lower with Ropivacaine. Patient satisfaction scores were significantly better with Ropivacaine. Conclusion: Although chloroprocaine use resulted in shorter discharge times, Ropivacaine was associated with better analgesia, reduced analgesic requirements and better patient satisfaction, which might make it a more attractive alternative.
Authors and Affiliations
Dr. Mahendra Ekka
Keywords
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