A COMPARATIVE STUDY OF LIGNOCAINE, LIGNOCAINE WITH DEXMEDETOMIDINE AND LIGNOCAINE WITH KETAMINE FOR IVRA IN UPPER LIMB SURGERIES
Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2018, Vol 7, Issue 33
Abstract
BACKGROUND Dexmedetomidine and Ketamine have been shown to decrease anaesthetic requirements and to induce analgesia in patients. They have been used successfully in combination with local anaesthetics for procedures like spinal, epidural and brachial blocks. Aim- To evaluate the effects of dexmedetomidine and ketamine when added to lignocaine in IVRA. MATERIALS AND METHODS After Institutional approval and informed consent, 90 ASA 1 and 2 volunteers were taken into the study. In Group A, 30 patients were randomly allocated to receive IVRA for upper limb with 3 mg/kg of 0.5% lignocaine; in Group B, 30 patients randomly received IVRA of upper limb with 3 mg/kg of 0.5% lignocaine with 0.5 mcg/kg dexmedetomidine and Group C patients randomly received IVRA of upper limb with 3 mg/kg of 0.5% lignocaine with 0.5 mg/kg ketamine. The onset of sensory, complete motor block and tourniquet pain were assessed and any symptoms after cuff deflation were recorded. Usual haemodynamic monitoring was used. Statistical Analysis- ANOVA (Analysis of Variance) and Chi-square tests were used for data analyses; p value of <0.05 was considered significant. RESULTS Groups A, B and C were comparable in demographic and surgical parameters. The speed of onset of sensory and motor block was higher in Group C (Ketamine) (p < 0.0001). The tourniquet pain occurred significantly later in Group B (Dexmedetomidine) (p<0.0001). There were few incidences of bradycardia in Group B. CONCLUSION In conclusion, the present study suggested that dexmedetomidine and ketamine will modify the action of local anaesthetic, providing a shorter onset time of sensory and motor block and longer duration of action in IVRA.
Authors and Affiliations
Ravindra S. Giri, P. G. Raghavendra
Keywords
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- EP ID EP541588
- DOI 10.14260/jemds/2018/819
- Views 87
- Downloads 0
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