A Comparative Study of Oral versus Vaginal 25µg Misoprostol for Cervical Ripening and Induction of Labour in Prelabour Rupture of Membranes
Journal Title: Scholars Journal of Applied Medical Sciences - Year 2017, Vol 5, Issue 10
Abstract
Abstract: The objective of the study is to compare the safety and efficacy of equivalent doses of orally and vaginally administrated misoprostol in induction of labour in Primigravida at 37-42 weeks of gestation with vertex presentation with prelabour rupture of membranes. 100 patients divided in oral, 50 cases (mean gestational age group 37 weeks 2 days) and vaginal group, 50 cases (mean gestational age group 38 weeks 3 days) received Tab. 25 µg of misoprostol every 4 hourly either orally or digitally administered in the posterior fornix in the vaginal group. Maximum up-to 6 doses in both groups. Primary outcome of the study was induction delivery interval in oral group 22.90 hours and in vaginal group 17.38 hours. The mean BISHOP score for oral and vaginal group was 4.6 and 5.7 respectively after 8 hours of administration of misoprostol. Vaginal group requires less oxytocin augmentation for delivery. APGAR score at 1 minute in oral group was 7.56 and for vagina group was 7.48. NICU admissions are statistically not significant. The mean induction delivery interval was significantly shorter in vaginal group, the cause of which could be longer duration action, no first pass metabolism and direct action of vaginal misoprostol on uterus on cervix. In oral group failed induction was observed in 6% cases, whereas in vaginal group, no induction failure was observed. Vaginal misoprostol is more effective than oral misoprostol for induction of labour. Keywords:
Authors and Affiliations
Karuna Kanta Das, Bivarani G oswami, Abdul Hakim Anchari
Keywords
Related Articles
- EP ID EP372249
- DOI -
- Views 66
- Downloads 0
Depression, Anxiety and Stress Levels among Individuals with Siblings and Individuals without Siblings
The mental health wellbeing of single children has assumed relevance in the face of increasing single child families’ world over. This study was done on engineering college students using DASS questionnaire. The Depressi...
Role of Risk Malignancy Index in Predicting Ovarian Malignancy and its Correlation with Histopathological Report
The aim of this study was to evaluate the accuracy of the Risk Malignancy Index in discriminating between benign lesions and malignant adnexal masses in gynaecologic practice by correlating with the postoperative histopa...
Intussucseption: with specific lead point
Intussusception is a pathology in which telescoping of a proximal segment of bowel (intussusceptum) occurs into lumen of the distal segment (intus suscipiens). The bowel may simply telescope on itself (non pathological l...
Bull Horn Injuries-Rural problem in Urban India
Bull horn injuries are defined as lesions resulting from collision with bull/cow horns. Bull horn injuries though not so commonly seen in cities are commonly observed in rural areas. The injuries produced by bull goring...
Seroprevalence of TORCH Infections in Pregnant Women with Bad Obstetric History in and Around Bikaner, Northern Western Rajasthan
Abstract: The infections which are caused by Toxoplasma gondii, Rubella virus, Cytomegalovirus (CMV) and the Herpes Simplex Virus (HSV-2) during pregnancy are often associated with adverse foetal outcomes and reproductiv...